DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt8

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001037790.2	Gene:	ugt8 / 553508	ZFINID:	ZDB-GENE-060616-129	Length:	541	Species:	Danio rerio

Alignment Length:	541	Identity:	138/541 - (25%)
Similarity:	248/541 - (45%)	Gaps:	72/541 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDY 70
            ||.|.:.|....:.||.|:.:.....:||...|:.:..||...||:.........|.|.:|:  |
Zfish     7 LATLLWCLATSLSWAAKIVVVPPIMFESHLYIFKTLASALHAEGHDTVFLVSEGREIPPSNH--Y 69

  Fly    71 VFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFM----------LHDWGLRSCKVALNSPLITQ 125
            ..|..|.:.:.....:|        |..||...|.          :.|...::|...:.|..:.:
Zfish    70 RLQRYPGIFNSTSADDF--------LQSKVRNIFSGRLTALELFDILDHYSQNCDAVVGSTSVME 126

  Fly   126 LLKSPIRYDVILLEHFSND-CMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLP- 188
            .||.. .:|::|::  .|: |...:||:|.......|:..   |:...:|:|     .|::::|
Zfish   127 QLKRE-HFDLLLVD--PNEMCGFVIAHILGVQYAVFSTGL---WYPAEVGAP-----APLSYVPE 180

  Fly   189 ----YTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFG---------PGLPPINEIVK 240
                .||.|||..|:        .||...::::.....|:..::.         |.: .::::|:
Zfish   181 FNSLLTDHMSLFQRV--------ANTAVYLVSRFGVQFLVLPKYDRIMRKYNIQPSV-SMHDLVQ 236

  Fly   241 NTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLD-LLDRSPNGVIYISWGSMVNSN 304
            |:.|.::....||..|||..|:|:.|||:...|..||||.... :.|...:|.:.:|:|:.|  .
Zfish   237 NSRLWMLCTDMALEFPRPTLPHVVYVGGILTKPPSPLPQEFETWVKDTDEDGFVVVSFGAGV--K 299

  Fly   305 TLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNL----YTFDWLPQRDLLCHPKIRAFI 365
            .|.......|..::|:|.: ..:.|:..:      .||||    ...||:||.|||.....|||:
Zfish   300 YLSDDIAQKLAGALSRLPQ-RVIWRFSGV------PPSNLGNNTKLVDWMPQNDLLGQTNTRAFL 357

  Fly   366 SHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHI-TRGLRIILDKK 429
            |||||....||::.|||::..|.:||.:.....|:.:|.|::::::......: |..:.:|.||:
Zfish   358 SHGGLNSIYEAMYHGVPVVGVPLFGDHYDTMTRVQAKGMGIMLEWKRMSEEDLYTAMVNVITDKR 422

  Fly   430 FAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILF 494
            :.||.:..|:..:.:|..|:..|.:||.:::::.||.|::|....|....|..:||.:. :|:..
Zfish   423 YRERAQLLSQIHKDQPGHPVSRAVYWISYILRHRGAEHLRSAVYEIPTYQYFLLDVAMV-IGVCL 486

  Fly   495 LLI-VALRKLIKIFKTAFCRG 514
            ||. ..|.:::|..:....||
Zfish   487 LLTGYCLYRIVKFIQFRLGRG 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	127/498 (26%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	114/453 (25%)
ugt8	NP_001037790.2	UDPGT	22..500	CDD:330975	131/517 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584401
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.740