Protein Alignment Ugt36F1 and UGT1A3

DIOPT Version :9

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_061966.1
• Gene: UGT1A3 / 54659
• HGNCID: 12535
• Length: 534
• Species: Homo sapiens
• Alignment Length: 563
• Identity: 153/563 - (27%)
• Similarity: 257/563 - (45%)
• Gaps: 78/563 - (13%)

  Fly     4 LPLALLA----FLLRPKPNDAAHILGLFQHPGK--------SHFDFFRPMFLALAERGH------ 50
            :||..||    .||..:|         :...||        ||:...|.:...|..|||
Human     7 VPLPWLATGLLLLLSVQP---------WAESGKVLVVPIDGSHWLSMREVLRELHARGHQAVVLT 62

  Fly    51 -NISMY----SYFPLEKPVANYTDYVFQGMPL-LTDIVDLSNFESEWKPLGLPFKVPTYF----M 105
             .::|:    ::|.|.....::|...|....| .|.:.    ||:|       ..:..:|    |
Human    63 PEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLY----FETE-------HFLKKFFRSMAM 116

  Fly   106 LHDWGL---RSCKVAL-NSPLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIM 166
            |::..|   |||...| |..||..|  :...:||:|.:.. |.|.|.:|..|:.|.:........
Human   117 LNNMSLVYHRSCVELLHNEALIRHL--NATSFDVVLTDPV-NLCAAVLAKYLSIPTVFFLRNIPC 178

  Fly   167 PWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPG 231
            ...:|....|..:..:|......:|.|:.:.|:.|..:...::.:.:..:.|.. :|.:|.|...
Human   179 DLDFKGTQCPNPSSYIPRLLTTNSDHMTFMQRVKNMLYPLALSYICHAFSAPYA-SLASELFQRE 242

  Fly   232 LPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYI 295
            :..: :|:.:.|:.|....:.:..|||..||::.:||:.....|||.|.....::.| .:|::..
Human   243 VSVV-DILSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGEHGIVVF 306

  Fly   296 SWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPK 360
            |.||||:.  :|..|..|:..::.::.:   .:.|:...:......:|.....||||.|||.||.
Human   307 SLGSMVSE--IPEKKAMAIADALGKIPQ---TVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPM 366

  Fly   361 IRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-I 424
            .||||:|.|..|..|:|..||||::.|.:|||..|:..::.:|.||.::..:..|..:...|: :
Human   367 TRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAV 431

  Fly   425 ILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFW 489
            |.||.:.|.:.|.|...:.||:.|:.||.:|:|.|:::.||||::..|..:.|..|:|:||
Human   432 INDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDV---- 492

  Fly   490 LGILFLLIVALRKLIKIFKTAF-----C---RGKISRDTKTKT 524
              |.|||.|.|......||...     |   :|::.:..|:||
Human   493 --IGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKT 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	133/497 (27%)
		YjiC	38..461	CDD:224732	119/444 (27%)
UGT1A3	NP_061966.1	UDPGT	29..525	CDD:278624	143/522 (27%)
		egt	<262..508	CDD:223071	85/256 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150160
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840