Protein Alignment Ugt36F1 and UGT1A5

DIOPT Version :9

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_061951.1
• Gene: UGT1A5 / 54579
• HGNCID: 12537
• Length: 534
• Species: Homo sapiens
• Alignment Length: 538
• Identity: 147/538 - (27%)
• Similarity: 247/538 - (45%)
• Gaps: 69/538 - (12%)

  Fly    17 PNDAAHILGLFQHPGKSHFDFFRPMFLALAERGH-------NISMY----SYFPLEKPVANYTDY 70
            |.|.:|.|.:            |.....|..|||       .::||    ::|.|.....::|..
Human    35 PTDGSHWLSM------------REALRDLHARGHQVVVLTLEVNMYIKEENFFTLTTYAISWTQD 87

  Fly    71 VFQGMPLLTDIVDLSNFES--EWKPLGLPFKVPTYFM------LHDWGLRSCKVAL-NSPLITQL 126
            .|       |.:.|.:.:|  |.:.|.:.|......|      :|    |||...| |..||..|
Human    88 EF-------DRLLLGHTQSFFETEHLLMKFSRRMAIMNNMSLIIH----RSCVELLHNEALIRHL 141

  Fly   127 LKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTD 191
              ....:||:|.:.| :.|.|.:|..|:.|.:...........:|....|..:..:|......:|
Human   142 --HATSFDVVLTDPF-HLCAAVLAKYLSIPAVFFLRNIPCDLDFKGTQCPNPSSYIPRLLTTNSD 203

  Fly   192 EMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGP 256
            .|:.:.|:.|..:...::.|.:.::.|.. :|.:|.|...:..: ::|.:.|:.|....:.:..|
Human   204 HMTFLQRVKNMLYPLALSYLCHAVSAPYA-SLASELFQREVSVV-DLVSHASVWLFRGDFVMDYP 266

  Fly   257 RPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQ 320
            ||..||::.:||:.....|||.|.....::.| .:|::..|.||||:.  :|..|..|:..::.:
Human   267 RPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSE--IPEKKAMAIADALGK 329

  Fly   321 LKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLV 385
            :.:   .:.|:...:......:|.....||||.|||.||..||||:|.|..|..|:|..||||::
Human   330 IPQ---TVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVM 391

  Fly   386 TPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPPI 449
            .|.:|||..|:..::.:|.||.::..:..|..:...|: :|.||.:.|.:.|.|...:.||:.|:
Human   392 MPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPL 456

  Fly   450 KLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAF--- 511
            .||.:|:|.|:::.||||::..|..:.|..|:|:||      |.|||.|.|......||...
Human   457 DLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDV------IGFLLAVVLTVAFITFKCCAYGY 515

  Fly   512 --C---RGKISRDTKTKT 524
              |   :|::.:..|:||
Human   516 RKCLGKKGRVKKAHKSKT 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	133/489 (27%)
		YjiC	38..461	CDD:224732	120/444 (27%)
UGT1A5	NP_061951.1	UDPGT	29..525	CDD:278624	144/528 (27%)
		egt	<262..508	CDD:223071	85/256 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150158
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840