Protein Alignment Ugt36F1 and UGT1A6

DIOPT Version :9

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001063.2
• Gene: UGT1A6 / 54578
• HGNCID: 12538
• Length: 532
• Species: Homo sapiens
• Alignment Length: 577
• Identity: 142/577 - (24%)
• Similarity: 243/577 - (42%)
• Gaps: 121/577 - (20%)

  Fly     6 LALLAFLLRPK----PNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFP----LEK 62
            |||...::..|    |.|.:|.|.:            :.:...|::|||.|.:  ..|    |.|
Human    18 LALWGMVVGDKLLVVPQDGSHWLSM------------KDIVEVLSDRGHEIVV--VVPEVNLLLK 68

  Fly    63 PVANYTDYVFQGMPLLTDIVDLSN----------------------FESEWKPLGLPFKVPTYFM 105
            ....||..::   |:..|..:|.|                      :.:....:||      ||:
Human    69 ESKYYTRKIY---PVPYDQEELKNRYQSFGNNHFAERSFLTAPQTEYRNNMIVIGL------YFI 124

  Fly   106 LHDWGLRSCKVALNSPLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHY 170
                   :|:..|.........|.. ::|.:..:. :..|...:|..|..|.:           |
Human   125 -------NCQSLLQDRDTLNFFKES-KFDALFTDP-ALPCGVILAEYLGLPSV-----------Y 169

  Fly   171 KRMGSP------FINPIMPMNFLP-----YTDEMSLIDRLNNF-------FHFHTVNTLYNMITQ 217
            ...|.|      |.....|::::|     ::|.|:...|:.||       :.|:.:.:.|..:..
Human   170 LFRGFPCSLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELAS 234

  Fly   218 PATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLL 282
            ......:         .|..:.:..|:.|:...:.|..|||..||::.:||:.....|.|.|...
Human   235 AVLKRDV---------DIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFE 290

  Fly   283 DLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYT 346
            ..::.| .:|::..|.||||:.  :|..|..|:..::.::.:   .:.|:...:......:|...
Human   291 AYINASGEHGIVVFSLGSMVSE--IPEKKAMAIADALGKIPQ---TVLWRYTGTRPSNLANNTIL 350

  Fly   347 FDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFR 411
            ..||||.|||.||..||||:|.|..|..|:|..||||::.|.:|||..|:..::.:|.||.::..
Human   351 VKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVL 415

  Fly   412 DFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHI 475
            :..|..:...|: :|.||.:.|.:.|.|...:.||:.|:.||.:|:|.|:::.||||::..|..:
Human   416 EMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDL 480

  Fly   476 NWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAF-----C---RGKISRDTKTKT 524
            .|..|:|:||      |.|||.|.|......||...     |   :|::.:..|:||
Human   481 TWYQYHSLDV------IGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKT 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	124/513 (24%)
		YjiC	38..461	CDD:224732	111/468 (24%)
UGT1A6	NP_001063.2	egt	15..506	CDD:223071	135/550 (25%)
		UDPGT	27..523	CDD:278624	136/558 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150166
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740