Protein Alignment Ugt36F1 and UGT1A7

DIOPT Version :9

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_061950.2
• Gene: UGT1A7 / 54577
• HGNCID: 12539
• Length: 530
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 145/545 - (26%)
• Similarity: 241/545 - (44%)
• Gaps: 84/545 - (15%)

  Fly    27 FQHPGK--------SHFDFFRPMFLALAERGHNISMYSYFP---------LEKPVANY-TDYVFQ 73
            |...||        ||:...:.:...|..|||.:.:  ..|         |...|..| |.|..:
Human    22 FAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVV--VMPEVSWQLGRSLNCTVKTYSTSYTLE 84

  Fly    74 GMPLLTDIVDLSNFESEW-KPLGLPFKVPTYFM--LHDWGLRSCKVALNSPLITQLLKSPIRYDV 135
            ..    |...:...::.| .||...|.:.|...  :.|....:|:...|...:.:.||... :|.
Human    85 DQ----DREFMVFADARWTAPLRSAFSLLTSSSNGIFDLFFSNCRSLFNDRKLVEYLKESC-FDA 144

  Fly   136 ILLEHFSNDCMAAVAHLLNAPVIALSS---CAIMPWHYKRMGSPFINPI--MPMNFLPYTDEMSL 195
            :.|:.| :.|...||...:.|.:..:.   |     ||...|:....|:  :|...|.::|.|:.
Human   145 VFLDPF-DACGLIVAKYFSLPSVVFARGIFC-----HYLEEGAQCPAPLSYVPRLLLGFSDAMTF 203

  Fly   196 IDRL-NNFFH----------FHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQ 249
            .:|: |:..|          |..|..:.:.|.|....|.             ::..:||:.|:..
Human   204 KERVWNHIMHLEEHLFCPYFFKNVLEIASEILQTPVTAY-------------DLYSHTSIWLLRT 255

  Fly   250 HYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSA 313
            .:.|..|:|..||:|.:||:.....||:|......::.| .:|::..|.||||:.  :|..|..|
Human   256 DFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGEHGIVVFSLGSMVSE--IPEKKAMA 318

  Fly   314 LFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIH 378
            :..::.::.:   .:.|:...:......:|.....||||.|||.||..||||:|.|..|..|:|.
Human   319 IADALGKIPQ---TVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESIC 380

  Fly   379 CGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFR 442
            .||||::.|.:|||..|:..::.:|.||.::..:..|..:...|: :|.||.:.|.:.|.|...:
Human   381 NGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHK 445

  Fly   443 QRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIF 507
            .||:.|:.||.:|:|.|:::.||||::..|..:.|..|:|:||      |.|||.|.|......|
Human   446 DRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDV------IGFLLAVVLTVAFITF 504

  Fly   508 KTAF-----C---RGKISRDTKTKT 524
            |...     |   :|::.:..|:||
Human   505 KCCAYGYRKCLGKKGRVKKAHKSKT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	132/498 (27%)
		YjiC	38..461	CDD:224732	117/453 (26%)
UGT1A7	NP_061950.2	UDPGT	26..521	CDD:278624	141/531 (27%)
		egt	<264..504	CDD:223071	83/250 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150122
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740