DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and Ugt35C1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001097744.1	Gene:	Ugt35C1 / 53507	FlyBaseID:	FBgn0040256	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	512	Identity:	156/512 - (30%)
Similarity:	264/512 - (51%)	Gaps:	28/512 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLPLALLAFL---LRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFP-LE 61
            |:||.:..:.|.   .:|..:::|.||.....||:|.:.|......|||.:||.:::.:.|. .|
  Fly     1 MRLLTVIAIVFCALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINAFKNKE 65

  Fly    62 KPVANYTDYVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQL 126
            .|...:.: ..:......:::.|.|....|:.|.....:...|:         .|.:....:.:|
  Fly    66 TPNMRFIE-ALKAHEFADEMMSLLNVPLLWQQLNAMDYILNKFI---------DVTMEDEGVQRL 120

  Fly   127 LKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIM--PMNFLPY 189
            |.|...:|::|.|....:.|.|.|...||.::..||........:..|:  |:||.  |:...|.
  Fly   121 LNSGETFDLVLAEMLHMEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGN--ISPISYNPLVTSPR 183

  Fly   190 TDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALT 254
            ||.|:.::||.|.:.....:...:.:..|....:..:.|......:.|::.:.||:|:.||::|:
  Fly   184 TDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFPNAKKTLEEVMDSFSLILLGQHFSLS 248

  Fly   255 GPRPYAPNVIEVGGLQVG--PIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQS 317
            .||||.||:|||||:.:.  | ||||:.:...::.||:||||.|.||.|.|..||...|..|.::
  Fly   249 YPRPYLPNMIEVGGMHISHKP-KPLPEDIKQFIEGSPHGVIYFSMGSNVKSKDLPQETRDTLLKT 312

  Fly   318 ISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVP 382
            .::||:.   :.||..:.....:|:|:....|.||.|:|.||.::.||||||||.:||:::.|.|
  Fly   313 FAKLKQR---VLWKFEDDDMPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKP 374

  Fly   383 MLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIIL-DKKFAERVRRSSEAFRQRPI 446
            :|..|.:.||.:|....::.|||:.:|..:.....:.:.::.:| |..:|:.....||.:|.:|.
  Fly   375 ILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQ 439

  Fly   447 PPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGI---LFLLIVAL 500
            ..:..|.||.|:||::.||||:::.:|.:|:|..||:|.|...|.:   |.||||.|
  Fly   440 SAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTL 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	143/473 (30%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	125/428 (29%)
Ugt35C1	NP_001097744.1	egt	1..470	CDD:223071	143/484 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.960