DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and Ugt35E1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_652622.3	Gene:	Ugt35E1 / 53504	FlyBaseID:	FBgn0040253	Length:	527	Species:	Drosophila melanogaster

Alignment Length:	553	Identity:	172/553 - (31%)
Similarity:	281/553 - (50%)	Gaps:	78/553 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVAN-YTD 69
            |..|..||.|.....|.||.||..|..||:....|....||..||.|:..|.||.|:||.| |..
  Fly     6 LFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKNIYDI 70

  Fly    70 YVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYF-MLHDWGLRSCKVALNSPLITQLLKSP--I 131
            ||    |.:     |::|:...|.:..|.....:| ..:::.....|...|:..:.:.:..|  .
  Fly    71 YV----PEV-----LNSFDELLKQMTTPKNTWEFFDATNEFVYNITKDVFNNDGVRREILRPGKA 126

  Fly   132 RYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRM-GSPFINPIMPMNFLPYTDEMSL 195
            ::|:|:::.:..|...::|....||:|.|:.|.| .|....| |:|     .||::|  ....|.
  Fly   127 QFDLIIVDIWKYDAFYSLAAYFEAPIIGLAPCGI-DWKIDEMVGNP-----SPMSYL--QSPSSY 183

  Fly   196 IDRLNNF--------------FHFH-----TVNTLYNMITQPATDALIAERFGPGL---PPINEI 238
            :..|:.|              |::|     ....||             :::.|.:   .|::||
  Fly   184 LYNLDTFGGRVAHVVEVAISWFNWHWRYEQKHEALY-------------KKYFPKIAETKPLSEI 235

  Fly   239 VKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVG--PIKPLPQHLLDLLDRS-PNGVIYISWGSM 300
            .::.:|:|:|||:.|..||||.||||||||:.:.  | |.|.|.|.|.:..| .:||||.|.|:.
  Fly   236 SQDIALVLVNQHFTLGPPRPYVPNVIEVGGMHIDEQP-KALAQDLEDFIQGSGEHGVIYFSLGTN 299

  Fly   301 VNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQ----PSNLYTFDWLPQRDLLCHPKI 361
            |.:..:...::..|.::...|.:.   :.||    .||::    |||:....||||:|||.|||:
  Fly   300 VRTKNMVDDRKRILIEAFGSLPQR---VLWK----FEDEELQDIPSNVLVRKWLPQQDLLAHPKV 357

  Fly   362 RAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRG-LRII 425
            :.||:|||:..|.|:||.|.|||..||:.|||.|...:|:.||.:.:::.|..|:.:... |:::
  Fly   358 KLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLL 422

  Fly   426 LDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWL 490
            .:|:|....|.:...:|.:|:.|::.|.||..:|:::.||||::...|.:::..::|:|||...|
  Fly   423 TEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVLGTVL 487

  Fly   491 GILFLLIVALRKLIKIFKTAFCRGKISRDTKTK 523
            .::.|:|:|: .||.:|...    |||::..|:
  Fly   488 LVILLVIIAI-LLIIVFSVC----KISKNISTR 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	155/502 (31%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	139/457 (30%)
Ugt35E1	NP_652622.3	egt	6..461	CDD:223071	152/492 (31%)
Ugt35E1	NP_652622.3	UDPGT	33..484	CDD:278624	149/488 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454639
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890