DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and Ugt304A1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_652619.1	Gene:	Ugt304A1 / 53501	FlyBaseID:	FBgn0040250	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	498	Identity:	131/498 - (26%)
Similarity:	231/498 - (46%)	Gaps:	50/498 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PGKSHFD--FFRPMFLALAERGHNIS-MYSYFPLEKPVAN-------YTDYVFQGMPLLTDIVDL 84
            |.:||..  ...|...||.:|||.:: :::|......:.:       |.:.||..   ..:.|.:
  Fly    32 PFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMHKIEDVTFIRIWYNNNVFLE---FEESVGI 93

  Fly    85 SNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLKSPIRYDVILLEHFSNDCMAAV 149
            ::..::|:.:.....:.....|:         .||:..:..|:||.|.:|.::||...:|.:..:
  Fly    94 ASANNKWEEISSMSSLMANATLN---------VLNNVEVRALMKSRITFDAVVLEAGYSDVLYGM 149

  Fly   150 AHLLNAPVIALSSCAIMPWHYKRM----GSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTVNT 210
            |...:|.:|.:.:| :..|:...:    .|....||||.. ..|.  .::.||:.|:.:......
  Fly   150 AAHFSAQLIGICTC-VADWNINNLVGFSTSTLTEPIMPFR-AKYV--KNVWDRIYNWLYTTEEWL 210

  Fly   211 LYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIK 275
            |.|::..|....:....||......:||.::.:|||:|||::|...||..|.::||.||.:....
  Fly   211 LINLVFLPKQRLIHDHFFGHLEKSFHEIRQDFALMLLNQHFSLFRARPNVPGMVEVAGLHIPKED 275

  Fly   276 P-LPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSAL---FQSISQLKEYNFVMRWK----S 332
            | ||..|...:|.:.:|||..|.|...:|..||...:..|   |:|:.|.      :.||    |
  Fly   276 PQLPSDLQVFIDEAEHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQR------VIWKFDGES 334

  Fly   333 LESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSG 397
            ..||    .:::|....|||:.:|.||.::.||||.|::...||.:...|:|..|.:.|||.|..
  Fly   335 TMSL----GTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLE 395

  Fly   398 AVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIK 461
            .:|:.|..:.::........:...:. :|.:.::.|.....|:.||.:||.|:..|.:|.|::|:
  Fly   396 IMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIR 460

  Fly   462 YGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLI 504
            |.||.|::.....:....|.|:|..:. :|....|:|||..|:
  Fly   461 YKGADHMKISQSQLKLFDYYSLDNFIM-VGSRLSLVVALVFLV 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	125/479 (26%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	114/443 (26%)
Ugt304A1	NP_652619.1	egt	8..480	CDD:223071	122/473 (26%)
Ugt304A1	NP_652619.1	YjiC	42..445	CDD:224732	108/428 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454647
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.890