DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and RGD1559459

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_003751392.1	Gene:	RGD1559459 / 501907	RGDID:	1559459	Length:	530	Species:	Rattus norvegicus

Alignment Length:	537	Identity:	150/537 - (27%)
Similarity:	249/537 - (46%)	Gaps:	89/537 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SHFDFFRPMFLALAERGHNISM------YSY------------FPLEKPVANYTDYVFQGMPLLT 79
            ||:...:.:...|.::||.:.:      :||            ||....:|: .:.:|.
  Rat    34 SHWLNLKIILSELVKKGHEVVVLKPSVSFSYEVDKTSAIEFESFPSSYSIAD-VEVIFM------ 91

  Fly    80 DIVDLSNFE----SEWKPLGLPFKVPTYFML--------HDWGLRSCK-VALNSPLITQLLKSPI 131
            |.|:.|.:|    |.|          .||::        .|:..|.|: .|.|..|:|:|..|
  Rat    92 DCVNESIYELPKQSFW----------GYFLMLQKLFERTSDYSERLCRDAAFNKELMTKLQNS-- 144

  Fly   132 RYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWH-YKRM--GSPFINPIMPMNFLP----- 188
            .:||||.:.|: .|...:|.:|..|::  .|....|.. |::.  |.|     ||.:::|
  Rat   145 GFDVILADPFT-PCGDLLAEILKIPLV--YSLRFFPGSTYEKYSGGLP-----MPPSYVPIAMSE 201

  Fly   189 YTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFG-PGLPPINEIVKNTSLMLINQHYA 252
            .:|.|:.::|:.:..:....:..:.:..:...:.|..|..| |  ..::|.:....:.||..::.
  Rat   202 LSDRMTFVERVKHMIYVLCFDFWFQVFDEKKWNELYTEVLGRP--TTLSETMAKADIWLIRTYWD 264

  Fly   253 LTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQ 316
            |..|.|..||...||||...|.||||:.:.|.:..| .:||:..|.||||.|  |...:.:.:..
  Rat   265 LEFPHPVLPNFDFVGGLHCRPAKPLPKEIEDFVQSSGEHGVVVFSLGSMVGS--LTEERANVIAA 327

  Fly   317 SISQLKEYNFVMRWKSLESLEDKQP----SNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAI 377
            .::|:.:       |.|...|.|:|    ||...:.|:||.|||.|||.||||:|||..|..|||
  Rat   328 GLAQIPQ-------KVLWRFEGKKPETLGSNTRLYKWIPQNDLLGHPKTRAFITHGGTNGIYEAI 385

  Fly   378 HCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIIL-DKKFAERVRRSSEAF 441
            :.|:|::..|.:|||..|...:|.:|..|.:||....|..:...||.:. |..:.|...|.|...
  Rat   386 YHGIPVVGIPLFGDQKDNIVHLKTKGAAVRLDFLTMSSTDLLTALRTVTNDPSYKENAMRLSRIH 450

  Fly   442 RQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKI 506
            ..:|:.|:..|.:|||.|:::.||.|::.....::|:.|:|:||:.|.|..:..::..|:|.
  Rat   451 HDQPVKPLDRAVFWIEFVMRHKGAKHLRVAGHDLSWVQYHSLDVIGFLLACVVTVMFILKKC--- 512

  Fly   507 FKTAFCRGKISRDTKTK 523
              ..||..|.::..:.|
  Rat   513 --CLFCCQKFTKAGRKK 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	142/499 (28%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	132/468 (28%)
RGD1559459	XP_003751392.1	UDPGT	24..527	CDD:278624	149/535 (28%)
RGD1559459	XP_003751392.1	egt	<270..508	CDD:223071	87/246 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343994
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2882
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.790