DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and ugt2a1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_031759199.1	Gene:	ugt2a1 / 447975	XenbaseID:	XB-GENE-954008	Length:	735	Species:	Xenopus tropicalis

Alignment Length:	552	Identity:	149/552 - (26%)
Similarity:	244/552 - (44%)	Gaps:	99/552 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DAAHILGLFQHPGKSHFDFFRPMFLALAERGHNI-------------SMYSYFPLEK-PVANYTD 69
            ||:|.|.|            |.:...||.:||.:             ::.|....|. ||| :|.
Frog   238 DASHWLNL------------RLILEELAHKGHEVTALVHSANMLIDHNLPSALKAEVFPVA-FTK 289

  Fly    70 YVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHD---WGL-RSCKVALNSPLITQ----- 125
            ..|     ||...|..||   |           .:.:|:   |.| ...|||:.|.|..|
Frog   290 ETF-----LTLQRDFFNF---W-----------IYGVHNMSYWELYEHLKVAVASSLKLQRDTCD 335

  Fly   126 -LLKSP--------IRYDVILLEHFSNDCMAAVAHLLNAPVI---------ALSS-CAIMPWHYK 171
             :||:.        .::|:::.:..: .|...:|..|..|.:         :|.. |..:|
Frog   336 GVLKNKELMYKLQNQKFDIVVADPVA-PCGELIAESLGVPFVYSFRFSMGNSLERLCGQLP---- 395

  Fly   172 RMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFG-PGLPPI 235
               |||  ..:|.....::|:||...||.|...:...:.:::::.|...|...:|..| |.  .:
Frog   396 ---SPF--SYVPGAMTAFSDKMSFGQRLANTVLYAFQDLIFSLVFQKNWDNYYSEILGRPA--KV 453

  Fly   236 NEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGS 299
            .||:....:.||..::....|||..||...||||...|.||||:.:..:::.| .:|::..|.||
Frog   454 CEIMGKAEIWLIRTYWDFEYPRPILPNFKFVGGLHCAPAKPLPEEIEKVVESSGEHGIVVFSMGS 518

  Fly   300 MVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAF 364
            |:.:  ..:.:.:.:..::|||.:   .:.|:......|....|..|:||:||.|||.|||.:||
Frog   519 MIKN--FSNERTNIIAAALSQLPQ---KVLWRYSGKKPDALGENTITYDWIPQNDLLGHPKTKAF 578

  Fly   365 ISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDK- 428
            |:|||..|..|||:.|||::..|.:.:|..|...:|.:|..:::||....:..:...:..:::.
Frog   579 ITHGGTNGIYEAIYHGVPIVGIPLFAEQPDNIVHMKSKGMAIMLDFNKMGTQDLLDAVNTVINNP 643

  Fly   429 KFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGIL 493
            .:.|...|.|.....:|:.|:..|.:|||.|:::.||.|::..:..:.|..|:.:||:.|....|
Frog   644 TYKENAMRLSRIHHDQPVKPLDSAVFWIEFVMRHKGAKHLRPASHELTWYQYHCLDVIGFMFVCL 708

  Fly   494 FLLIVALRKLIKIFKTAFCRGKISRDTKTKTQ 525
            ||..     .|.|....||..|..|.||.|.|
Frog   709 FLFF-----YITITFLTFCYKKCCRTTKEKNQ 735

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	135/512 (26%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	123/467 (26%)
ugt2a1	XP_031759199.1	UDPGT	238..733	CDD:278624	147/548 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000