DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and Ugt303B2

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	146/505 - (28%)
Similarity:	245/505 - (48%)	Gaps:	40/505 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LPLALLAFLLRPKPN------DAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEK 62
            |..|.|||.|....|      .||:|||:|.:...|.|...||:..||.||||.::|.:  |.:.
  Fly     3 LGYAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVT--PADY 65

  Fly    63 PVANYTDYVFQGMPLLTDIVD--LSN---FES---EWKPLGLPFKVPTYFMLHDWGLRSCKVALN 119
            | |.........:|:|..::.  :.|   |::   :|:. |:......|.:.|        ..||
  Fly    66 P-AKIDGVRHIRVPMLNQLMQNLMKNDQFFDALGDKWRE-GVLVSTIFYNVSH--------AILN 120

  Fly   120 SPLITQLLK-SPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMG---SPFI-N 179
            :..:..|:: ..||:|:|::|....|.:..:|...||.::.: ||..|.||...:.   :|.: .
  Fly   121 NNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGI-SCMHMTWHIDYLAGNLAPSVYE 184

  Fly   180 PIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSL 244
            ||.|..|   ..:.:.:.|.:|:.:......|..::.:||...|..:.||.....::|:....|:
  Fly   185 PISPNGF---ALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEKLDELRARFSV 246

  Fly   245 MLINQHYALTGPRPYAPNVIEVGGLQVG-PIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPS 308
            :|:|.|:::...|...||:|||.|:.:. |.:|....|...||.:.:|.||.|.|..:....||.
  Fly   247 ILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPE 311

  Fly   309 GKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGT 373
            ..:..|.....|:|:.   :.|||..|:...:..|:|..|.:|||.:|.||.:|.||:||||...
  Fly   312 NMQKQLLLVFLQMKQR---VIWKSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSV 373

  Fly   374 TEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDK-KFAERVRRS 437
            .|||..|||||..|.:.|||.|...|:..|...::|..|.:::.:...::.:|:. .:|:|.:..
  Fly   374 MEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEM 438

  Fly   438 SEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLL 487
            :.:||.||:.|:..|.||.|:.::.....|::.....|..:.|..:|.:|
  Fly   439 AASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSIL 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	138/482 (29%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	126/437 (29%)
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	134/458 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454644
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890