DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and Ugt303B1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	165/532 - (31%)
Similarity:	260/532 - (48%)	Gaps:	55/532 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVFQ 73
            |..||:.....||:|||:|.:...|.|...:|:...||.||||:::.:      |:
  Fly    12 LCLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLIT------PI--------- 61

  Fly    74 GMPLLTDI-----VDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVA----------LNSPLI 123
            |||  .||     :.::......|.: |.......||::.| ..|...|          |:.|.:
  Fly    62 GMP--NDIEGVRHIRVAQLNERIKEM-LESDQVLDFMINKW-TESALTAKALFNASNDILSDPGV 122

  Fly   124 TQLL--KSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWH-YKRMGSP---FINPIM 182
            .::|  ||. .:|:|::|..|.|.:..:....||.::.|||..| .|| |:..|:|   ...||.
  Fly   123 QRMLHDKSE-SFDLIIMEPSSLDALYGLVEFYNATLMGLSSIRI-NWHTYELAGNPAPSIYEPIS 185

  Fly   183 PMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLI 247
            |:.|   :.|.||..|:.|:.|......:..:|.:||...|..:.||.....:||:....|||||
  Fly   186 PVGF---SLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLI 247

  Fly   248 NQHYALTGPRPYAPNVIEVGGLQVG-PIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKR 311
            |.||::...|..|||:||||||.:. |.:|..:.|...||::.:||||.|.|:.:....||...:
  Fly   248 NSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQKFLDKADHGVIYFSMGNDILIKFLPENIQ 312

  Fly   312 SALFQSISQLKEYNFVMRWKS-LESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTE 375
            ..|.|:.:.|.|   .:.||| |..:.||. .|:|..:..|||.:|.||.:|.||::||||...|
  Fly   313 ELLLQTFATLNE---SIIWKSELLYMPDKS-DNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIE 373

  Fly   376 AIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSE 439
            |:..|||||..|.:.|||.|...|:..|...::|....:.:.:|..:: ::.:..:..:.:..|:
  Fly   374 AVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQ 438

  Fly   440 AFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLI 504
            .|:.||:.|:..|.||.|:.::......::.....|..|.|..||.:|.: .:.|.|:.|  .||
  Fly   439 FFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAF-SLRFGLVAA--SLI 500

  Fly   505 KIFKTAFCRGKI 516
            .:..|.|.:.:|
  Fly   501 FLVYTLFLKYRI 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	153/491 (31%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	140/446 (31%)
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	148/468 (32%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	153/500 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454643
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890