DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and Ugt316A1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001287111.1	Gene:	Ugt316A1 / 40079	FlyBaseID:	FBgn0036842	Length:	636	Species:	Drosophila melanogaster

Alignment Length:	517	Identity:	144/517 - (27%)
Similarity:	252/517 - (48%)	Gaps:	52/517 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AHILGLFQHPGKSHFDFFRPMFLALAER--GHNISMYSYFPLEKPVANYTDYVFQGMPLLTDIVD 83
            |::|.:|....|||:.|.|.:...|.|.  .|::::.|....::.|.       ..:|.:.:: .
  Fly    19 ANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVD-------AEIPKIREL-R 75

  Fly    84 LSNFESEWKPLGLPFK---------VPTYFMLHDWGLRSCKVALNSPLITQLLKSPIRYDVILLE 139
            :......|..:|:.|:         :..:..|...|..:..:.|:.|.:.:||.|..::|:::::
  Fly    76 IEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILLSDPQVRKLLTSGEKFDLLIVD 140

  Fly   140 HFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTDE-----------M 193
            .|.:|.:..:|.....|.:|:|......|.....|:|..:.:.|.||||:|:.           |
  Fly   141 LFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSNFLPFTERMNTRQRILNSLM 205

  Fly   194 SLIDRLN-NFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPR 257
            |..:||. ||||..:..::|.    ...:.|:.|     ||...::.||.||.|||.|..|..||
  Fly   206 STFERLTYNFFHLISQQSVYT----NHFELLVKE-----LPLYRDLTKNLSLALINSHPGLHYPR 261

  Fly   258 PYAPNVIEVGGLQVGPIKP--LPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQ 320
            .|.||::|||||.:..:..  ||:|||..::.:|:||||.|.|:.|.:..||..|.:.:......
  Fly   262 AYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESAPSGVIYFSLGADVETAQLPQEKLAIILDVFGH 326

  Fly   321 LKEYNFVMRWKSLE-SLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPML 384
            |||::|:::|:..| :.|...|.|:...||.||:.:|.||:::.|||..|.|...|:|....|:|
  Fly   327 LKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVL 391

  Fly   385 VTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPP 448
            ..|...:|.:.:..:::.|..|.|.:.....:.:..|:| :.|:..:.|::.:..|....|...|
  Fly   392 AIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTP 456

  Fly   449 IKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLF----WLGILFLLIVA----LRK 502
            :..|...|:.:::.|||..::|.|..:|:.....:||||.    :.|||.:..:|    |||
  Fly   457 VGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVDVLLIIAVGFFGILTIPFLAICFILRK 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	135/492 (27%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	120/449 (27%)
Ugt316A1	NP_001287111.1	egt	1..480	CDD:223071	131/477 (27%)
Ugt316A1	NP_001287111.1	MGT	39..448	CDD:273616	114/425 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454651
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	6	5.940