DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and Ugt317A1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001286734.1	Gene:	Ugt317A1 / 37590	FlyBaseID:	FBgn0040091	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	537	Identity:	141/537 - (26%)
Similarity:	230/537 - (42%)	Gaps:	80/537 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDY 70
            ||:|...| .:.:.||.||.||.|..:.||...|.:...||.|.|.|.:|:...|.:.:.|.|:.
  Fly    11 LAILGLAL-GQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGLGESLDNVTET 74

  Fly    71 VFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFM---LHDWGLRSCKVALNSPLITQLLKS--- 129
            |....|..:::...:..:.....|||   :|...:   |...|.|:....|....|.:|||.
  Fly    75 VTAEFPFWSELQKQAAPKGNLADLGL---LPIEKLRQSLASVGARALDHFLAQEPIQKLLKMSYL 136

  Fly   130 PIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSC-----------AIMPWHYKRMGSPFINPIMP 183
            ...:||||:::|..:.:.|:..|...||:.:.|.           |::|           ....|
  Fly   137 EFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALVP-----------AACSP 190

  Fly   184 MNFLPYTDEMSLIDRLNN----------FFHFHTVNTLYNMITQPATDALIAERF--GPGLPPIN 236
            ::|.....|||...||.|          |...|     |.     ..:.|:.:.|  ...:|.:.
  Fly   191 IDFERDQPEMSFSVRLGNIRTCIARRKQFIKDH-----YG-----GQEQLVTKYFQLQSSIPELQ 245

  Fly   237 EIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMV 301
              ....|::|:|.|..|..|:.....:|..|||.:...|.||.::...|:.:..|.||:..|:..
  Fly   246 --ASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEARPGAIYVQLGNEQ 308

  Fly   302 NSNTLPSGKRSALFQSISQLKEYNFVMRW-----KSLESLEDKQPSNLYTFDWLPQRDLLCHPKI 361
            ....||..|...||...|..|:   .:.|     |:||.|    |.|:.....:||.|:|.||::
  Fly   309 ACGQLPKEKLDTLFAFFSARKQ---SIIWTCHDVKTLEGL----PKNVMIQHAVPQIDILAHPRV 366

  Fly   362 RAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGL---- 422
            :||:::|.||...|.|...||:|..|.:..:..|.....:.|.|:.::    :.|..|..|
  Fly   367 KAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLE----EGNVTTESLNWAV 427

  Fly   423 -RIILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVL 486
             |::|:..|...:|..|..||.||:..:..|.:|:.:|.::.|...:::....|:....:..|:.
  Fly   428 DRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLF 492

  Fly   487 LFWLGILFL---LIVAL 500
            :|:.||..|   |:|||
  Fly   493 VFYAGIATLVVSLLVAL 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	129/506 (25%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	117/461 (25%)
Ugt317A1	NP_001286734.1	Glycosyltransferase_GTB_type	22..477	CDD:299143	127/491 (26%)
Ugt317A1	NP_001286734.1	UDPGT	25..514	CDD:278624	136/522 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.060