DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and Ugt49C1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001036565.1	Gene:	Ugt49C1 / 37421	FlyBaseID:	FBgn0034605	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	164/522 - (31%)
Similarity:	252/522 - (48%)	Gaps:	62/522 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPV--ANYTDYVFQGMPLLTDI 81
            :.:.||.::..||||||.....:...|.|.||.::|.:.|.|||..  :|||:.      |:..:
  Fly    23 EGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQLGSNYTEI------LIEPV 81

  Fly    82 VDLSNFESEWKPLGLPFKVPTYF------------MLHDWGLRSCKVALNSPLITQLLKSPIR-- 132
            .|.      |..:.|.|.....|            ||...||::.:.||..|.:..|:.:..:
  Fly    82 YDF------WHDVKLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHAEQKEG 140

  Fly   133 -YDVILLEHFSNDCMAAVAHLLNAPVIALSSCA-----------IMPWHYKRMGSPFINPIMPMN 185
             :|::|.|.|..:...|:|||...||:..|:..           |.||.:           :|..
  Fly   141 VFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPWSF-----------VPHG 194

  Fly   186 FLPYTDEMSLIDRLNNFF--HFHTVNTLYNMITQPATDALIAERFGPGL---PPINEIVKNTSLM 245
            |:|:||.||.::|:.|.:  .:..::.|.|..  |..||:..|.|||.|   |.:..:.:..|:|
  Fly   195 FMPFTDRMSFLERVKNSYASFYEDMDRLLNYF--PKMDAVAREFFGPVLTEVPKVKHMERQISVM 257

  Fly   246 LINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGK 310
            |:|.|..||..||....::.|||:.:.|.||||..:..|||.:..|.|:.|.||.|.|..:|...
  Fly   258 LLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLPADMQALLDGATEGAIFFSLGSNVQSKDMPVEM 322

  Fly   311 RSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTE 375
            .....|....||:.   :.||..:....:.|.|:....||||.|:|.|..::.||:||||.||.|
  Fly   323 LRLFLQVFGSLKQR---VLWKFEDESISQLPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQE 384

  Fly   376 AIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGL-RIILDKKFAERVRRSSE 439
            .:|..||||..|||.||.||.......|:.:.:.|:......:...| ::|.:..:.|.|:|.|:
  Fly   385 GVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSD 449

  Fly   440 AFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLI 504
            .||.||:.|.|.|.:|||:||::.||.|::|....:||..:..:||:.|...|....::||...|
  Fly   450 IFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVMALSLAI 514

  Fly   505 KI 506
            ::
  Fly   515 RL 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	159/501 (32%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	142/456 (31%)
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	161/508 (32%)
Ugt49C1	NP_001036565.1	UDPGT	37..498	CDD:278624	154/488 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454693
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890