DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and Ugt37A1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_523607.2	Gene:	Ugt37A1 / 35307	FlyBaseID:	FBgn0026756	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	561	Identity:	150/561 - (26%)
Similarity:	248/561 - (44%)	Gaps:	88/561 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANY 67
            :|.|.||.:     ....|:|||||.....||......:...|||:|||:::.:..   :|...:
  Fly    12 VLALTLLIY-----GAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVL---EPTITH 68

  Fly    68 TDYVFQGMPLLTD--------------------IVDLSNFESEWKPLGLPFKVPTYFMLHDWGLR 112
            .:.....:|:..:                    .:.:.|...:.                |..||
  Fly    69 KNINLVTVPMTKEEIKQRSETIGAKQKNTSSNRFISILNMSGQM----------------DSMLR 117

  Fly   113 SCKVALNSPLITQL-LKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSP 176
            .....|....:.:| |.....:|:::..:|.||.....|..:||||:.|:...........:|:|
  Fly   118 KMADVLKDQRVKELYLNKDNHFDLVISGYFMNDYQLGFARKVNAPVVVLAPSPPSQMLNSLIGNP 182

  Fly   177 F--INPIMPMNF----------LPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFG 229
            .  :.....|.|          |.|...:..||:.|..:        ||            |.||
  Fly   183 HDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQY--------YN------------EIFG 227

  Fly   230 --PGLPPINEIVKNTSLMLINQHYALTGP-RPYAPNVIEVGGLQV-GPIKPLPQHLLDLLDRSPN 290
              |.:|...:|::||||:....|.|..|| ||..|..||:||:|: ....|||::|...|..:.:
  Fly   228 DDPTMPEYTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNATH 292

  Fly   291 GVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDL 355
            |.|.:|.||.|..:.:.:.....:|..:|.||: ..:.:|..|:....|..:.||: .||||.|:
  Fly   293 GAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQ-RVIWKWDDLDKTPGKSDNILYS-RWLPQDDI 355

  Fly   356 LCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITR 420
            |.||.::.||:|.|..|.:||.:.|.|||..|.:|||..|:.|:.:.|||:.:.....:......
  Fly   356 LAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRA 420

  Fly   421 G-LRIILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSID 484
            . |.|:.:.|:::||.:.|..:|.||....:...:|.|:||::.||.|:||...|:::|..|::|
  Fly   421 AVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLD 485

  Fly   485 VLLFWLGILFLLIVALRKLIKIFKTAFCRGKISRDTKTKTQ 525
            :......|...|::.|:|:::|    .||...::..|.|.|
  Fly   486 IYALIGAISIGLLLMLKKVVQI----TCRRLRTKLNKVKKQ 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	136/505 (27%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	118/460 (26%)
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	123/471 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454657
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	7	6.940