DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and Ugt2b7

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_775445.2	Gene:	Ugt2b7 / 286989	RGDID:	708417	Length:	529	Species:	Rattus norvegicus

Alignment Length:	513	Identity:	135/513 - (26%)
Similarity:	244/513 - (47%)	Gaps:	43/513 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SHFDFFRPMFLALAERGHNISMY----SYFPLEKPVANYTDYVFQGMPLLTDIVDLSNFESEWKP 93
            ||:...:.:...|.:|||.:::.    |.|...|..:.   .|::..|..::..::..|.::|..
  Rat    34 SHWMNLKIILDELVQRGHEVTVLRPSSSVFLDPKKASG---LVYETFPTTSNNDEVEKFFTQWVN 95

  Fly    94 LGLPFKVPTYFMLH-------------DWGLRSCK-VALNSPLITQLLKSPIRYDVILLEHFSND 144
            . ..:.||.|..|.             |..|:.|: |..|..|:.:|.:|  ::||:|.:.. ..
  Rat    96 T-WTYDVPKYTCLRYYPSLNKMFGQFSDLWLQLCREVVSNKHLMAKLKES--QFDVVLSDAV-GP 156

  Fly   145 CMAAVAHLLNAPVIALSSCAIMPWHYK-RMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTV 208
            |...:|.:|..|.:......|.....| ..|.||....:|:.....:.:|:.::|:.|.......
  Rat   157 CGELIAEILQLPFVYSLRFGIGYGIEKYSAGQPFPPSYVPIILSGLSGQMTFMERVENMLCLLYF 221

  Fly   209 NTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGP 273
            :..:........|...:|..|.....: :.:|...:.||..::.|..|||..||:..||||...|
  Rat   222 DFWFESFPAKDWDPFFSEILGRPTTMV-DTMKKAEIWLIRSYWDLEFPRPSLPNIEFVGGLHCQP 285

  Fly   274 IKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLE 337
            .||||:.:.|....| .:||:..|.|||:.:.|  ..:.:.:..:::|:.:..|   |:    .|
  Rat   286 AKPLPKEMEDFAQSSGEHGVVVFSLGSMIRNIT--QERANTIASALAQIPQKVF---WR----FE 341

  Fly   338 DKQPS----NLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGA 398
            .|:|.    |...|.|:||.|||.|||.:||::|||..|..|:||.|:||:..|.:.:|..|...
  Rat   342 GKKPDTLGPNTRVFKWIPQNDLLGHPKTKAFVTHGGANGIYESIHHGIPMVGIPLFAEQRDNVAH 406

  Fly   399 VKQRGFGVIVDFRDFDSNHITRGLRIILDK-KFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKY 462
            :..:|..|.:||....|:.:...|:.:::| .:.::|...|.....:|:.|:..|.:|||.|:::
  Rat   407 MVAKGAAVSLDFHTMSSSDLLNALKAVINKPSYKKKVMWLSAIHHDQPLKPLDRAVFWIEFVMRH 471

  Fly   463 GGAPHIQSEARHINWIVYNSIDVLLFWLG-ILFLLIVALRKLIKIFKTAFCRGKISRD 519
            .||.|::..|.::.|..|:|:||:.|.|. :|.::::|::..:.:::......|..||
  Rat   472 KGAKHLRPLAHNLAWYQYHSLDVIGFLLACVLAIVLLAVKCCLFLYRFFVKVAKNKRD 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	128/478 (27%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	117/447 (26%)
Ugt2b7	NP_775445.2	UDPGT	24..527	CDD:278624	133/509 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2882
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860