DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and F10D2.8

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001309630.1	Gene:	F10D2.8 / 266913	WormBaseID:	WBGene00017334	Length:	494	Species:	Caenorhabditis elegans

Alignment Length:	523	Identity:	117/523 - (22%)
Similarity:	227/523 - (43%)	Gaps:	83/523 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GKSHFDFFRPMFLALAERGHNISMYSYFPLEK-PVANYT----DYVFQGMP--LL-----TDIVD 83
            |.||..||..:..||.:.|||::.::...:|| ...:||    |.|....|  |:     .:..|
Worm    27 GHSHTKFFATIADALTDAGHNVTFFTPTIVEKYRNVSYTKLTKDVVHMDAPKKLMEYGEQMESAD 91

  Fly    84 LSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLKSPIRYDVILLEHFSNDCMAA 148
            .|.|.:|         ..:::.:....|..|.:.||.     |.||.:  |.:.::.|
Worm    92 FSRFWTE---------DSSFYNVGAADLYRCSIRLNG-----LFKSLM--DYLNIKTF------- 133

  Fly   149 VAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTVN---- 209
                  .|.::|:....:.   |.:|.|.:..::.....|:.|::||::|..|.|....::
Worm   134 ------IPSLSLTHDVYLS---KAIGEPVMPSVVSDVCSPFGDKLSLLERAFNAFAVPYIDIVLG 189

  Fly   210 -TLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGP 273
             .::|.::.|.|:.           .|..|....|.:.:|.:..|..|||.....:|:||:.|..
Worm   190 YPVHNTLSAPYTEI-----------DIRTIEPEASFLFLNSNPFLDFPRPTLTKTVEIGGITVDL 243

  Fly   274 IKPLPQHL-------LDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWK 331
            .:...|.|       |:|.:::    :.:|:||:..|..:|...:..:..|:::.|...|:.:::
Worm   244 NQLKSQQLDSKWSDILNLREKT----MLVSFGSVFFSKDMPLENKKVIANSMTEFKNVTFIWKYE 304

  Fly   332 SLESLED--KQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFL 394
            . ..:||  :...|::...|:||..||.:.::.||.:|.||....|..:.|.|.::.|.:.||..
Worm   305 G-NDIEDFARGIQNIHFVKWVPQTALLANRRLSAFFTHAGLGSINEVSYLGKPSILCPLFADQMR 368

  Fly   395 NSGAVKQRGFGVIVDFRDF-DSNHITRGLRIIL-DKKFAERVRRSSEAFRQRPIPPIKLATWWIE 457
            |:..:.:....:.:...|. :|..|....:.|| |..:||..::.:|....:||.|.|:.....|
Worm   369 NAKMLVRHNGSIELSKYDLGNSKKIIEAFQAILFDSSYAENAQKLAEQLENQPIKPEKMMVKHAE 433

  Fly   458 HVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCRGKISRDTKT 522
            ...::|..|.:...:|.::::.|..:||....:.:|..::..|.::::.    .||..:   .|.
Worm   434 FAARFGRLPSLDPYSRKMSFVEYFLLDVATICVLVLACVVFVLTRVVQF----LCRRFL---VKI 491

  Fly   523 KTQ 525
            ||:
Worm   492 KTE 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	110/483 (23%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	100/450 (22%)
F10D2.8	NP_001309630.1	UDPGT	29..492	CDD:278624	114/517 (22%)
F10D2.8	NP_001309630.1	Glycosyltransferase_GTB_type	<215..461	CDD:299143	59/250 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161360
Domainoid	1	1.000	172	1.000	Domainoid score	I2232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.740