DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and Ugt2b

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_113721.5	Gene:	Ugt2b / 24862	RGDID:	3936	Length:	530	Species:	Rattus norvegicus

Alignment Length:	539	Identity:	146/539 - (27%)
Similarity:	256/539 - (47%)	Gaps:	72/539 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 HPGK--------SHFDFFRPMFLALAERGHNISMY---SYFPLEKPVANYTDYVFQGMPLLTD-- 80
            |.||        ||:...:.:...|.:|||.:::.   :||.|:...::...:......:..|
  Rat    22 HCGKVLVWPMDFSHWMNIKIILDELVQRGHEVTVLKPSAYFFLDPKKSSDLKFEIFSTSISKDEL 86

  Fly    81 ------IVDLSNFE------SEWKPL--GLPFKVPTYFMLHDWGLRSCKVAL-NSPLITQLLKSP 130
                  ::|:..:|      ..:.|:  .|.::. :||.     |..||.|: |..|:|:|.:|
  Rat    87 QNHFIKLLDVWTYELPRDTCLSYSPILQNLVYEF-SYFY-----LSICKDAVSNKQLMTKLQES- 144

  Fly   131 IRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWH--YKRMGSPFINPIMPMNFLP----- 188
             ::||:..:..:: |...:|.||:.|.  |.|.:..|.|  .|.:|. |   |:|.:::|
  Rat   145 -KFDVLFADPVAS-CGDLIAELLHIPF--LYSLSFSPGHKLEKSIGK-F---ILPPSYVPVILSG 201

  Fly   189 YTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFG-PGLPPINEIVKNTSLMLINQHYA 252
            ...:|:.|||:.|.......:..:.::.....|...:|..| |  ..::|.:....:.||..::.
  Rat   202 LAGKMTFIDRVKNMICMLYFDFWFEILRHKEWDTFYSEILGRP--TTVDETMSKVEIWLIRSYWD 264

  Fly   253 LTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQ 316
            |..|.|..|||..:|||...|.||||:.:.:.:..| .:||:..|.||||::.|  ..|.:|:..
  Rat   265 LKFPHPTLPNVDYIGGLHCKPAKPLPKDMEEFVQSSGEHGVVVFSLGSMVSNMT--EEKANAIAW 327

  Fly   317 SISQLKEYNFVMRWKSLESLEDKQPS----NLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAI 377
            :::|:.:       |.|...:.|.|:    |...:.||||.|:|.|||.:||::|||..|..|||
  Rat   328 ALAQIPQ-------KVLWKFDGKTPATLGPNTRVYKWLPQNDILGHPKTKAFVTHGGANGLYEAI 385

  Fly   378 HCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDKKFAER-VRRSSEAF 441
            :.|:||:..|.:|||..|...:..:|..|.::.|..........|..::|..|.:: |...|...
  Rat   386 YHGIPMIGIPLFGDQPDNIAHMVAKGAAVSLNIRTMSKLDFLSALEEVIDNPFYKKNVMLLSTIH 450

  Fly   442 RQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKI 506
            ..:|:.|:..|.:|||.::::.||.|::....::.|..|:|:||:.|.| ..|.:|.||.....:
  Rat   451 HDQPMKPLDRAVFWIEFIMRHKGAKHLRPLGHNLPWYQYHSLDVIGFLL-TCFAVIAALTVKCLL 514

  Fly   507 FKTAFCRGKISRDTKTKTQ 525
            |...|.   :.::.|.|.:
  Rat   515 FMYRFF---VKKEKKMKNE 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	136/499 (27%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	123/456 (27%)
Ugt2b	NP_113721.5	UDPGT	24..527	CDD:278624	143/532 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2882
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860