DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and ugt-3

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_506203.2	Gene:	ugt-3 / 191174	WormBaseID:	WBGene00013903	Length:	529	Species:	Caenorhabditis elegans

Alignment Length:	547	Identity:	121/547 - (22%)
Similarity:	233/547 - (42%)	Gaps:	95/547 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GKSHFDFFRPMFLALAERGHNISM-----YSYFPLEKPVANYTDYVFQGMPLLTDIVDLSNFE-- 88
            |.||..|...:...||:.|||:::     |.|:..:|.|.|..             :::.|:|
Worm    26 GYSHMKFMGRIADILADAGHNVTLFQPIIYDYYAHKKIVKNPN-------------IEVINYEVD 77

  Fly    89 SEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLIT-------------QLLKSPIRYDVILLEH 140
            .|.|.......|..:|    |..:..|..::|..||             ::|.....:..||.::
Worm    78 EEEKAAASEASVFKFF----WKAKGSKNPISSAKITSEKLYKEFEHICRKMLLDKELHRWILSKN 138

  Fly   141 FSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPF--------------INPIMPMNFLP--- 188
            |.       :|:..    |...|.:....:.::.||.              :...:|:|:||
Worm   139 FD-------SHISE----AFDFCGLYLGDFLKLKSPIPLYSGVRCGAASYAVGEPIPLNYLPTEG 192

  Fly   189 --YTDEMSLIDRLNNF-----FHFHTVNTLYNMITQPATDALIAERF-GPGLPPINEIVKNTSLM 245
              |..:.|.||||::.     :||.     :.::.....|.  |.|. |..:....||:::::..
Worm   193 SNYGKKSSAIDRLSDMLGLTGYHFQ-----FGILFDKQYDQ--AYRLTGGNVRTWQEILQSSTFF 250

  Fly   246 LINQHYALTGPRPYAPNVIEVGGLQVGPIK--PLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPS 308
            |.|.:..|:...|....||::||..:...|  .|.:....:|... |..|.:|:|:::.|:.:|.
Worm   251 LTNSNPYLSFSTPTISKVIQIGGFTIESFKTTTLDEEFNKILSLR-NNTILVSFGTVIQSSDMPD 314

  Fly   309 GKRSALFQSISQLKEYNFVMRWKSLE---SLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGL 370
            ..::.|.::..::.:..|:  ||..|   :|::|...|:....|:||..||...::..|::||||
Worm   315 DFKTGLIEAFRRMPDATFI--WKYEEDDKTLKNKLSENVVLSKWIPQPALLADSRLDLFVTHGGL 377

  Fly   371 LGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDF-DSNHITRGLRIILDKK-FAER 433
            ..|.|..:.||..::.|.:.||.:|:..:.:.|..::.|..|. ||..:...:::||:.. :.:.
Worm   378 GSTMEVGYAGVSSIMVPVFSDQGVNAEMLARHGGAIVYDKFDLVDSKKLMETIQMILNNSDYRKN 442

  Fly   434 VRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIV 498
            .:|.|:....:|:.|.::.....|...::....:::..|...|:|.:..:|.|.  |.:..:.:|
Worm   443 SKRLSDILHNQPMDPKQVLLNHCEFAARFAQVDNLEPYANKYNFIEFYCLDSLA--LVVCTISVV 505

  Fly   499 ALRKLIKIFKTAFCRGKISRDTKTKTQ 525
            || .:.||.  :|....:....|.|.:
Worm   506 AL-VMFKIL--SFVVNSVIEKLKLKKE 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	111/507 (22%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	103/474 (22%)
ugt-3	NP_506203.2	egt	1..457	CDD:223071	105/468 (22%)
ugt-3	NP_506203.2	UDPGT	27..525	CDD:278624	118/540 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810