DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-54

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_501996.2	Gene:	ugt-54 / 188885	WormBaseID:	WBGene00012013	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	547	Identity:	133/547 - (24%)
Similarity:	228/547 - (41%)	Gaps:	74/547 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMY-----SYFPLEKPVA-- 65
            ||.||:.|...:..:||.......:||..|.......|.:|||.:.:.     ....|:.|..
Worm     4 LLGFLILPGFANCLNILFYVSVIAQSHIPFHNTAIKVLLDRGHTVDLVIAQLNEMVKLKFPNGVG 68

  Fly    66 -NYT------DYVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLI 123
             |||      ::..:....|:||.           :..|..:..:....|.....|:..:..|.:
Worm    69 KNYTFGYEDPNFYRKNAGHLSDIF-----------VEKPIPMAEFLTFDDMTFNLCETVVKDPNL 122

  Fly   124 TQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLP 188
            ...:|.. .||:.|...: :.|...:.|....|    |..:::|       :|...|.:....||
Worm   123 LNYIKQG-NYDIGLSSDY-DPCANILMHAGGVP----SKASMVP-------TPLFQPQIVSAGLP 174

  Fly   189 YTDEM-----------SLIDRLNNFFHFHTVNTLYNM-ITQPAT----DALIAERFGPGLPPINE 237
            ....:           |..:||     ||.:...||: ...|..    :.|:.|.|||..|...|
Worm   175 SPASVYGTVLYPKGDDSFFNRL-----FHLIRHTYNIYFVAPRLMEKYNNLLLETFGPTFPSAEE 234

  Fly   238 IVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVN 302
            |.:|..::|:|.:..:..|||.:..:..:||:.....:||.:...|:|..|..||:..|:|:.|.
Worm   235 IERNVDIILVNSNEIIEKPRPVSHKIKYIGGMGKKKAQPLNKEFNDILATSNKGVVLFSFGTQVA 299

  Fly   303 SNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQ----PSNLYTFDWLPQRDLLCHPKIRA 363
            ::.:|...|.....:.....:::|:  ||.....:|.:    .||::..:||||.|||...:::|
Worm   300 TSKVPIEIRKNFVTAFKHFPDFSFL--WKYDNLTDDAELFADSSNIHRVEWLPQTDLLGDNRVKA 362

  Fly   364 FISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGL-RIILD 427
            ||||.||....|....|:|:|..|.:.||..|:.....|..||||:.......::...| :::.:
Worm   363 FISHMGLNSFLETSAAGIPVLAVPLFIDQQHNALNAVSRDIGVIVERHQLTVENLVNALQKLLYN 427

  Fly   428 KKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQS-EARHINWIVYNSIDVLLFWLG 491
            .|:.|..:..|:...::|....:|...|:|:..|..|...|.: ....:....|.|:||
Worm   428 PKYGENAKMISKMMNEKPEQSERLFVDWVEYAAKNPGLHKIMNLPGAELTPFWYYSVDV------ 486

  Fly   492 ILFLLIVALRKLIKIFKT-AFCRGKIS 517
            ||.:::.....||.|:|| :|.:.:||
Worm   487 ILIVVLSLTSSLIIIWKTLSFIKCQIS 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	118/503 (23%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	106/457 (23%)
ugt-54	NP_501996.2	UDPGT	35..507	CDD:278624	120/508 (24%)
ugt-54	NP_501996.2	egt	<218..498	CDD:223071	78/287 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810