DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and ugt-56

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_506074.2	Gene:	ugt-56 / 188073	WormBaseID:	WBGene00011453	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	543	Identity:	121/543 - (22%)
Similarity:	209/543 - (38%)	Gaps:	122/543 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVFQ---GMPLLTDIVDLSNFESE--- 90
            :||..|...:...||.|||.:::             .|.||:   ...|.:||.::.:.|..
Worm    30 QSHVYFTARIANVLAARGHKVTV-------------IDNVFRYDVDNELSSDIHEIISVEPSPEV 81

  Fly    91 -------------WKPLGLPFKVPTYF--MLHDWGLRSCKVALNSPLITQLLKSPIRYDVILLEH 140
                         |.....|.:..|..  :.|...|:...:..||.||.:|  ..|::|..:.|.
Worm    82 TKLLNTGSLPTILWNSKASPEEQRTIMEGLGHVHRLQCTHLIENSTLIPKL--QEIKFDFAIHEV 144

  Fly   141 FSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLN----- 200
            | :.|...:..     ||.:....|            ::...||:.:|.|  :.:.|.||
Worm   145 F-DSCGVGILE-----VIGVQKTVI------------VSSTGPMDVVPIT--LGISDTLNTPSLL 189

  Fly   201 -------NFF-------------HFHTVNTLYNMITQPATDALIAERFGP--GL-PPINEIVKNT 242
                   :||             :||.:.           |::|:..|..  || .|..||::..
Worm   190 SDYGSYLSFFEKRRNLKFLSGMLNFHEMQ-----------DSMISPLFKKYYGLKKPTGEIMRQA 243

  Fly   243 SLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLP 307
            :|:..|.|....|.|.......::||:.....|.|......||. .|...:.:|:|:...|:.:|
Worm   244 NLLFYNIHEGSDGMRMRGRRSFDIGGIAFKDQKNLTMEYQTLLS-DPRPKVLVSFGTAATSSHMP 307

  Fly   308 SGKRSALFQSISQLKEYNFVMRWKSLESL--EDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGL 370
            ...:::|..::.|:....|:.:::..::.  :::..:|:....:|||.|||...||..|::|.|.
Worm   308 QNLKNSLMTAMKQMNNVLFIWKYEMEDNFTKQEELTTNIIFKKFLPQTDLLASSKIDLFVTHCGQ 372

  Fly   371 LGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDS-----NHITRGL-------- 422
            ....||.:.||.:|..|.:|||..|:....:.|...|:...|.::     ..:..||
Worm   373 NSLLEAFNSGVRVLAVPLFGDQHRNAKLAFENGLIEILPKSDIETPAKIVKAVKTGLEPNAKLDQ 437

  Fly   423 RIILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIV--YNSIDV 485
            .|:|   .:..:|.|.|......|..|: ||:..|....:...|    :..|.|.:|  .:|...
Worm   438 NIVL---ISSLLRNSKENAENLLISTIE-ATYSTEFPPNFSKFP----KNYHPNTLVRLIDSSIA 494

  Fly   486 LLFWLGILFLLIVALRKLIKIFK 508
            |:|.| .:|:.:...||....||
Worm   495 LVFML-FIFVFVNHFRKNYVGFK 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	113/520 (22%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	105/486 (22%)
ugt-56	NP_506074.2	Glycosyltransferase_GTB_type	<216..>399	CDD:299143	49/194 (25%)
ugt-56	NP_506074.2	Glycosyltransferase_GTB_type	<353..453	CDD:299143	30/102 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161450
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740