DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and ugt-32

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_504060.2	Gene:	ugt-32 / 185911	WormBaseID:	WBGene00018543	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	513	Identity:	120/513 - (23%)
Similarity:	220/513 - (42%)	Gaps:	68/513 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVFQGMPLLTDIVDLSNFES-EWKPLGL 96
            ||.:|...:...|.|.|||::.::      |:.:.:.....|:.|..|::.|...|. :..|:.:
Worm    32 SHTNFMARLADTLTEAGHNVTFFT------PIIDESRKDQFGVKLTKDVLILEQDEQVKRNPVTI 90

  Fly    97 PFKVPTYF---------------MLHDWGLRSCK-VALNSPLITQLLKSPIRYDVILLEHFSNDC 145
            ...: .||               .||...:.:|: |..:..||.:|...  .||:.|.|......
Worm    91 DNDM-KYFWTTDVTSANGHKVMGTLHKQAIFTCENVFKHQELIDELRSR--NYDIGLAEPLMTCG 152

  Fly   146 MAAVAHLLNAPVIALSSCA----IMPWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFH 206
            :|...|:....|:..:||.    ::|    ..|.|......|......||.||...||.|:..:|
Worm   153 LALFRHIGIEKVMLTTSCTNYDILLP----ATGEPEDTSYNPSMNSQVTDVMSFWQRLENYDLYH 213

  Fly   207 ----TVNTLYNMITQPATDALIAERF-GPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEV 266
                |..|:::      .:|.:..:: |...|...:::.:.||...|....|..|||.....||:
Worm   214 VMIPTFETIFD------DEANVYRKYLGESFPDWRDLIPDASLHFTNSIPFLDFPRPSIQKTIEI 272

  Fly   267 GGLQVG--PIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMR 329
            ||:.|.  .|.|:.:...::||:.|..:: ||:||:..|..:|...:..|.:.........|:.:
Worm   273 GGIAVDIESIPPVNEEFSNILDKRPMNML-ISFGSLARSTEMPIIFKENLLRVFQSEPNCTFIWK 336

  Fly   330 WKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFL 394
            ::|.:........|:....|:||..:|...::.||::||||..|.||...|.|.::.|.:.||..
Worm   337 YESDDVAFANDVENVIFVKWMPQTAILKDNRLTAFLTHGGLGSTNEAAFLGKPSVMFPIFADQSR 401

  Fly   395 NSGAVKQRGFGVIV---DFRDF----DSNHITRGLRIILDKKFAERVRRSSEAFRQRPIPPIKLA 452
            ||..:.::...:::   |..:|    |:.|     .|:.::|:....|:.::..|.:|..|..:.
Worm   402 NSNMLGRQEMSIVLHKSDLGNFQKIRDAFH-----EILHNEKYHLNARKVADMVRNQPAKPRDIF 461

  Fly   453 TWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLF------WLGILFLLIVALRKLI 504
            ...:|.|.::|...|:...:..:.:......|:.:|      ::.::|||.|.  |||
Worm   462 VKHVEFVGRFGPLHHMTPYSLKMPFYQRYHYDIFIFKFLTNYFIPVVFLLCVT--KLI 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	112/488 (23%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	106/457 (23%)
ugt-32	NP_504060.2	Glycosyltransferase_GTB_type	1..508	CDD:299143	113/500 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161465
Domainoid	1	1.000	172	1.000	Domainoid score	I2232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.790