DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-41

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_504818.2	Gene:	ugt-41 / 184295	WormBaseID:	WBGene00017336	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	515	Identity:	112/515 - (21%)
Similarity:	212/515 - (41%)	Gaps:	63/515 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GKSHFDFFRPMFLALAERGHNISM-----------YSYFPLEKPVANYTDYVFQGMPLLTDIVDL 84
            |.||..|...:..:|.|.|||:::           .||....|.:........|..  ||:.::.
Worm    29 GHSHSTFMGKLADSLTEAGHNVTVLSIIISSKFRNISYTKSTKDIVVVETTTEQDQ--LTENMEN 91

  Fly    85 SNFESEWKPLGLPFK-VPTYFMLHDWGLRSCKVALNS---------PLITQLLKSPIRYDVILLE 139
            .:|...|...|...: :|:|.|.       .|:|.:.         |.:..|..:..:||.:..|
Worm    92 DDFARYWTQEGTMLETIPSYLMF-------LKMAEDGYKTFRDHALPQMDYLKNNRPQYDAVFFE 149

  Fly   140 HFSNDCMA-AVAHLLNAPVIALSSCAIMPWHYKRM-GSPFINPIMPMNFLPYTDEMSLIDRLNNF 202
            .|.  .|. |:...|..||....:.....:.:..: |.|.....:...|..:.:.|:..:||.|.
Worm   150 SFF--FMGKAIQEYLEIPVFLPVTSITHDYRFAELIGEPVSPSYLSGYFTNFGNIMNFQERLTNT 212

  Fly   203 FHFHTVNTL-----YNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPN 262
            ..::....|     :..:..|:.|.|:...:           .....:.||.:..:..|||....
Worm   213 ISYYLGQILIAFPNWKTLQDPSKDLLVESEY-----------HRAPYVFINSNPYIDFPRPLLSK 266

  Fly   263 VIEVGGLQVGPIKPLPQHLLD-----LLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLK 322
            .||:||:.| .:|.|....:|     :|.:.|:.|: ||:|||..|..:|...:..:.:.:...|
Worm   267 TIEIGGITV-DVKKLKSEKVDEKWDNILKKRPHNVL-ISFGSMFKSIYMPDFYKENMVKVMKSFK 329

  Fly   323 EYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTP 387
            ..:|:.:::|.|:.......|:....|:||..||...::.||.:||||....|..:.|.|.|:.|
Worm   330 NVSFIWKYESEETSFANGAENIIFSKWVPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCP 394

  Fly   388 FYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGL--RIILDKKFAERVRRSSEAFRQRPIPPIK 450
            .:.||..||..:.:....:.:...:.::.:..|..  .|:..:.::|...:.::....:|..|.:
Worm   395 LFADQIRNSKMLTRHNGSIEISKFNLENYNTLRSALHSILFAESYSENAEKLAKKLEYQPTKPKE 459

  Fly   451 LATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFW----LGILFLLIVALRKLIKI 506
            |.....|...::|..|...|..|.:.:..|..:||:.|.    |.::|::.:.:|:::|:
Worm   460 LFVRHAEFAARFGEQPAQDSNLRTMGFAAYYLLDVIAFLTSFVLLVIFVVFIMIRQIVKL 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	107/490 (22%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	96/457 (21%)
ugt-41	NP_504818.2	UDPGT	22..510	CDD:278624	110/504 (22%)
ugt-41	NP_504818.2	Glycosyltransferase_GTB_type	26..512	CDD:299143	110/506 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161523
Domainoid	1	1.000	172	1.000	Domainoid score	I2232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.740