DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-40

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_504810.2	Gene:	ugt-40 / 184292	WormBaseID:	WBGene00017331	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	556	Identity:	131/556 - (23%)
Similarity:	236/556 - (42%)	Gaps:	82/556 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISM-----------YSYFPLEK 62
            |.:||......:.:||......|.||..||..:...|.|.|||:::           |||..|.|
Worm     8 LYYLLLISSTTSYNILVFCPLFGHSHSTFFGRLADILTEAGHNVTLFSPTIIDEFRNYSYTKLTK 72

  Fly    63 PVANYTDYVFQGMPLLTDIVDL-SNFESEWKPLGLPFKVP--TYFMLHDWGLRSCKVALNSPLIT 124
            .|| |.|    ..|.|..|.|| :..:..|......|::|  |.|.......::..:|.|..|:.
Worm    73 DVA-YLD----PSPELKAIGDLIAGNKRWWNQEFSVFEIPQTTRFFKSITREQNNVLANNLALLD 132

  Fly   125 QLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPY 189
            .|.:.  ::|:||.|......:..:.:|.........|.|..|.....:|...:...:|......
Worm   133 GLKQK--KFDLILFESVFTCALPLMEYLEIKSFAVAQSIAYEPITLGALGDTVMTSHIPNLMAQS 195

  Fly   190 TDEMSLIDRLNNFFHFHTVNTL--------------YNMITQPATDALIAERFGPGLPPINEIVK 240
            :|:|||.:|:        :|||              |...|.|.......|:           :.
Worm   196 SDKMSLCERM--------LNTLIQAMLNVYGMTPEYYQSYTNPEKKIYTLEK-----------LS 241

  Fly   241 NTSLMLINQHYALTGPRPYAPNVIEVGGLQV--------GPIKPLPQHLLDLLDRSPNGVIYISW 297
            ..|.:.:|.:..|..||......|::||:.|        |.:......:|:|.:::    :.:|:
Worm   242 EASFIFMNSNPFLDFPRATITKNIQIGGISVNLDTLKSSGKLTEEWDQILNLREKT----LLVSF 302

  Fly   298 GSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQP-----SNLYTFDWLPQRDLLC 357
            ||::.|..:|...:..|..::.||.:..|:.:::.    :||:.     .|::...|:|||:||.
Worm   303 GSVILSQDMPFAYKVGLTNAMKQLNDVTFIWKYEG----DDKKEFANGIKNIHFSKWVPQRELLA 363

  Fly   358 HPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNH---IT 419
            .|::.||::||||....|..:.|.|.::.|..|||..|:..:::....  ::|..:|.::   :.
Worm   364 DPRLSAFMTHGGLGSVNEVSYFGKPTIMCPLSGDQMRNAKMLERHNGS--IEFSKYDLHNEKVVA 426

  Fly   420 RGLR-IILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSI 483
            ...| |:.|:.:....:|.||..:.:|:.|.:|....:|...::|..|.:...:|.:.:|.|..|
Worm   427 NAFRKILYDESYTLSAKRLSEHLQFQPVKPKELFLKHVEFAARFGKLPSLDPYSRQMGFIQYFLI 491

  Fly   484 DVLLFWLGILFLLIVALRKLIKIFKTAFCRGKISRD 519
            |:....|.::..::..|..::| |..:..:.||..|
Worm   492 DIAFIVLTVVLTIVSVLYFVLK-FVASCLKAKIKTD 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	121/512 (24%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	108/467 (23%)
ugt-40	NP_504810.2	YjiC	22..447	CDD:224732	108/460 (23%)
ugt-40	NP_504810.2	Glycosyltransferase_GTB_type	<247..503	CDD:299143	64/265 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161361
Domainoid	1	1.000	172	1.000	Domainoid score	I2232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.740