DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-65

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_502373.3	Gene:	ugt-65 / 184205	WormBaseID:	WBGene00008583	Length:	509	Species:	Caenorhabditis elegans

Alignment Length:	526	Identity:	121/526 - (23%)
Similarity:	221/526 - (42%)	Gaps:	69/526 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVF 72
            |||..|  ..::.:.||.|.....|||.....|:...|.:.||::|||:.      .||......
Worm    13 LLAHFL--TTSNCSRILFLNMFNSKSHALTMMPLAERLFDDGHDVSMYTI------SANRLKIPS 69

  Fly    73 QGMPLLTDIVDLSNFESEWKPLG------LPFKVPTYF--MLHDWGLRSCKVALNSPLITQLLKS 129
            :.:.:|..:|..|:.:......|      ..:::..|.  ..::.||...:...:..| .::|.:
Worm    70 KKVKILESLVKGSSTDDAAPDTGGVSRIFWSYEMTPYVGAWCYEIGLYYLEEGRDEQL-DEVLAT 133

  Fly   130 PIRYDVILLEHFSNDCMAAVAHLL----NAPVIALSSCAIMP-----WHYKRMGSPFINPI-MPM 184
            |  ||:.:::........::|..|    :..:|..::..:||     ..|.|      ||: :|.
Worm   134 P--YDLAVVDETYTSLQGSIALKLKEDHSTKIITFATTELMPVASNMRGYAR------NPVTVPN 190

  Fly   185 NFLPYTD-----EMSLIDRLNNFFHFH-------TVNTLYNMITQP---ATDALIAERFGPGLPP 234
            .||..::     ..:.:.|....|.:.       .|.:||:..:..   .|.|..::.|...:..
Worm   191 TFLLSSEVYEGNRFAFLTRTRRIFEYFIDQIYSGPVASLYSEASGKLLGLTSATKSKTFQNSILT 255

  Fly   235 INEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLL-DRSPNGVIYISWG 298
            :|:.....|.:           :|...::|.||........ ||....|.: |....|.||::.|
Worm   256 VNDFPDTFSFV-----------QPRGNDLIRVGEHCYSSAN-LPSEFRDFVEDSMSKGTIYVAMG 308

  Fly   299 SMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRA 363
            |.:|....|.|...|..::::..|:|..:  |....::...: .::.:.:|.||::||.|.|..|
Worm   309 SYLNLEDGPKGTVEAFIEALNYFKDYRVI--WSHKGNVTGAK-CHVKSVNWAPQKELLAHEKTVA 370

  Fly   364 FISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGL-RIILD 427
            ||:||||....|.:..|||||..||||||..|:......|....:..:...|..|.:.| ::::|
Worm   371 FITHGGLKSAKEGVCSGVPMLFLPFYGDQPRNAHRFVTNGIAEALYKKAITSLDIQQKLEKLLVD 435

  Fly   428 KKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHI--NWIVYNSIDVLLFWL 490
            ..:...|.:....:...||..:.|..:.|..|::...:.:.:.:.|.|  |.:.|.::|:.|..|
Worm   436 PSYKNNVMKVLSYYLDAPISSLDLGAFHISQVLRRTESQYSKFKRRSIFMNHLQYLNLDIFLVIL 500

  Fly   491 GILFLL 496
            .|||::
Worm   501 VILFIV 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	112/504 (22%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	101/457 (22%)
ugt-65	NP_502373.3	egt	<300..505	CDD:223071	59/207 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010