DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-27

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_491436.1	Gene:	ugt-27 / 182508	WormBaseID:	WBGene00015694	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	541	Identity:	131/541 - (24%)
Similarity:	232/541 - (42%)	Gaps:	56/541 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANY 67
            ||....|.|||..:.| :.::|........||.:|...:...|.|.|||::..      .|:.:.
Worm     2 LLFFYFLRFLLIFQVN-SINVLVYSPAFAASHTNFMARLADTLTEAGHNVTFL------VPIVDV 59

  Fly    68 TDYVFQGMPLLTDIVDL--------------SNFESEWKPLGLPFKVPTYFMLHDWGLR-SCKVA 117
            ......|:.:.||::.:              .:.|:.|........|...|.....|:: .|:..
Worm    60 ARTKQLGVHVTTDVIIVEKDEHTTQESVPFDDSMEAYWTEETHSSNVGESFQWFFDGMKLGCENL 124

  Fly   118 LNSPLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIM 182
            |....|...|||. .:||.::|..|...:.....|.....|..||||...:.::.:|.|.::..:
Worm   125 LRRHEILDQLKSR-NFDVAIVEPLSVCGLGLAKKLEIGKTILASSCAYYDYLFRHIGEPDVHSYL 188

  Fly   183 PMNFLPYTDEMSLIDRLNNFFHFHTV-----NTLYNMITQPATDALIAERFGPGLPPINEIVKNT 242
            |.......|.|:..:||.|    |.|     ..:|.|.  .:..|:..:.||..:|...:::...
Worm   189 PSLMSTTGDVMTTFERLEN----HRVAEAMATAMYKMF--DSEKAIYRKHFGDEIPDWRDLLPAA 247

  Fly   243 SLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVI-------YISWGSM 300
            ||...|.:..|..|||.....:.:||:.|...|...|.    ||:..|.::       .||:|||
Worm   248 SLYFTNSNPYLDFPRPILQKTVSIGGISVDTKKIKSQE----LDKEWNHILNKRNLNMLISFGSM 308

  Fly   301 VNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFI 365
            ::|:.:....:..|.:.|.......|:.::::.::.......|:|...|:||..||...::.||:
Worm   309 IHSSHMLDDAKKNLIKVIKSEPNVTFIWKYETNDTSFAFGIDNIYFSKWVPQSKLLNDARLTAFL 373

  Fly   366 SHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGL--RIILDK 428
            :||||..|.|..|.|.|.::.|.:|||:.|...:::.|..:||...:..:..|....  .::.|:
Worm   374 THGGLGSTNELAHFGKPAVMVPIFGDQYRNGHMLQRHGCAIIVQKTELSNWKIVSSAVKSVLYDE 438

  Fly   429 KFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVL---LFWL 490
            .:.:.....::..:.:|:.|.::...::|.|.::|..|.:.:..|.:|:|..|.:||.   ||..
Worm   439 NYKKNAAHLADLLQNQPVKPKEIVVKYVEFVARFGPFPEMDAYGRQLNFIQRNLLDVYLIELFGH 503

  Fly   491 GILFLLIVAL------RKLIK 505
            .:.||:|..|      |.|||
Worm   504 FLFFLIIFCLIPLQLKRWLIK 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	114/499 (23%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	102/451 (23%)
ugt-27	NP_491436.1	UDPGT	21..500	CDD:278624	114/495 (23%)
ugt-27	NP_491436.1	egt	<230..478	CDD:223071	61/251 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161463
Domainoid	1	1.000	172	1.000	Domainoid score	I2232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790