DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and ugt-11

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_504311.1	Gene:	ugt-11 / 178882	WormBaseID:	WBGene00020593	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	553	Identity:	130/553 - (23%)
Similarity:	236/553 - (42%)	Gaps:	99/553 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLLPLALLAFLLRPKPNDAAHILGLFQHP--GKSHFDF-----------------FRPMFLALA 46
            |:||..:.|.|||  |.|.||.|| :| :|  |.||..|                 |:|..|||.
Worm     1 MRLLTFSCLCFLL--KVNYAAKIL-IF-NPIFGFSHVKFVSKLADIIADHGQEVTLFQPFHLALK 61

  Fly    47 E-----RGHNISMYSYFPLEKPVANYTDYVFQGMPLLTDIVDLSNFESEW--------------- 91
            .     :..||.:.:|:|     .:|.|       ||.  ::...|...|
Worm    62 NLDGIVKNKNIEIINYYP-----DHYDD-------LLK--LETQTFPDFWDSQLMNNPVLMAFML 112

  Fly    92 -KPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLK--SPIRYDVILLEHFSNDCMAAVAHLL 153
             :.||..||..|..::.|               .::||  ...::||.:.|.|....| .::|.|
Worm   113 PRILGGEFKKTTIQLIKD---------------KEILKKLKDKKFDVAISETFELTGM-YMSHFL 161

  Fly   154 NAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQP 218
            ..|.|.:.|...:....:..|.......:.........:...:||||:.:........:..:.|.
Worm   162 GVPCIPILSAVRLDIFNEAFGQSSAFGYLTQQGSKLAPDAGFLDRLNDVYRDFFSKMAFRGMAQY 226

  Fly   219 ATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGL-----QVGPIKPLP 278
            ..| :|.:..|..:|...::||...:.:.|.:..|....|....::.:||:     ::..:..||
Worm   227 QND-VIEKAAGHVVPYWKDLVKEAPVYMTNSNPYLDFAVPTTATIVHIGGITINLEKMNHVDALP 290

  Fly   279 QHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWK-SLESLE--DKQ 340
            :. .:::.:.....:.||:||::.|..:|...::.|.:....|.:..|:  || .::.||  .|.
Worm   291 EE-YEIILKEKETTVLISFGSVIRSYEMPENFKAGLIKVFESLPDVIFI--WKYEIDDLEFQKKL 352

  Fly   341 PSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFG 405
            |.|::...|:||..||...:::.|::||||..|.|..:.|.|.|:.|.:|||.:|:..:.:.|..
Worm   353 PKNVHLKKWVPQPSLLADKRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPMNADMLARHGGA 417

  Fly   406 VIVDFRDF-DSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHI 468
            :..|..|. |...:|..:| ::.:.|:.::.:...:....:||.|:......:|..||:   |::
Worm   418 IAYDKFDLVDGKKLTETVRDLVTNPKYEQKAKELLDVLTNQPIDPVMNLMKHLEFAIKF---PNL 479

  Fly   469 QSEARHINW---IVYNSIDVLLFWLGILFLLIV 498
            :|:...||.   |.:..:||::|   ::|:.|:
Worm   480 RSQIPEINQVGPIAHYYLDVIVF---LIFVSII 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	118/522 (23%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	99/455 (22%)
ugt-11	NP_504311.1	egt	<220..514	CDD:223071	73/300 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.740