DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-53

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_503771.1	Gene:	ugt-53 / 178744	WormBaseID:	WBGene00020182	Length:	515	Species:	Caenorhabditis elegans

Alignment Length:	532	Identity:	130/532 - (24%)
Similarity:	220/532 - (41%)	Gaps:	89/532 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 HILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVFQGMPLLTDIVDL-- 84
            :||..:...|.||..:.|.....|..||||:.:  .|.:...:||        :.|..|:..:
Worm    18 NILFYYAVIGPSHIAYLRNTIGKLLARGHNVDV--VFAVYNELAN--------LDLFPDVRRIYY 72

  Fly    85 ----------------SN-FESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLKSPIR 132
                            || ||....|||      .:.:.|:.|.:.||:|:|...:.:.|||. :
Worm    73 NRHADPDYWKKNANHFSNMFEKSPTPLG------EFEIFHESGYQLCKIAINDLKLIEFLKSG-K 130

  Fly   133 YDVILLEHFSND---C---------MAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMN 185
            ||:    .||:|   |         :.::..|:..|:       .:| |....|.|.:..:...:
Worm   131 YDI----GFSSDYDPCGNILMTAAGIPSIGSLIATPI-------FLP-HIVSAGLPTVASVYGTS 183

  Fly   186 FLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDA----LIAERFGPGLPPINEIVKNTSLML 246
            ..|..|. ||.|::.|....    |.|:....|..|.    ||.:|||...|.:..|.:...::.
Worm   184 LYPEHDS-SLYDKIFNLIRL----TYYHYAISPDMDRKYNNLITKRFGNNFPDVGTIERGIDIIF 243

  Fly   247 INQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKR 311
            :|.|..|...||.:|.:..:||:.:...|.||.....:|....:..:..|:|:.|.:..:|...|
Worm   244 VNSHDFLEQQRPMSPKIKYIGGMAIRKAKQLPDEFEKILSVPKSAYVLFSFGTQVPTAKMPLPIR 308

  Fly   312 SALFQSISQLKEYNFVMRWKSLESLED--KQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTT 374
            .....:..:.....|:.::.|||...|  :...|::..:||||.:||...:::.||||.||....
Worm   309 RNFVGAFKKFPNVTFLWKYDSLELDADIFQGVENIHRLEWLPQTELLHDNRVKLFISHMGLNSYL 373

  Fly   375 EAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDK-KFAERVRRSS 438
            |....|||:|..|.:.||..|:...:.||.|:::|.....:.:|...|..:|:. |:....|..|
Worm   374 ETATAGVPVLSIPLFADQQNNAQNTRDRGMGLLLDRDKLTTKNIESALHELLENPKYLSNARSIS 438

  Fly   439 EAFRQRPIPPIKLATWWIE---------HVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILF 494
            :...::|.........|:|         .|:|..||        .::...|...|:||....|||
Worm   439 KMILEKPDKANDTFIHWLEFTARNPGLGRVLKLPGA--------ELSPFYYYCGDILLLVFCILF 495

  Fly   495 LLIVALRKLIKI 506
            :::..:.:.|.:
Worm   496 IILHTVLRTINL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	124/511 (24%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	114/469 (24%)
ugt-53	NP_503771.1	UDPGT	29..497	CDD:330975	126/509 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14449
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810