DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-29

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001370778.1	Gene:	ugt-29 / 178581	WormBaseID:	WBGene00021709	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	519	Identity:	121/519 - (23%)
Similarity:	218/519 - (42%)	Gaps:	60/519 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SHFDFFRPMFLALAERGHNISMYSYFPLEKP--------VANYTDYVF-----------QGMPLL 78
            ||.:|...:...|.|||||::.  ..|:..|        |....|.|.           :|:.|.
Worm    30 SHSNFLGKLADTLTERGHNVTY--LMPVMDPGKRDECIGVKLTKDLVIVEADEEMMSREEGVTLD 92

  Fly    79 TDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLR-SCKVALNSPLITQLLKSPIRYDVILLEHFS 142
            .:|::|     .||...........|...:..:: :|:..|....|.:.:||. .:||.::|..|
Worm    93 EEIMEL-----YWKSEMDSSNSRDMFSFFNNAMKAACRNFLKRRDIFEQMKSR-NFDVAIVEPLS 151

  Fly   143 NDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHT 207
            ...:..|..|.....|..|||.........:|.|.....:|..|....|.|::.:|..|:.....
Worm   152 VCGLGFVKALGIEKTILASSCTFYDSIMDYIGEPLDFSYVPALFSVTGDVMTMSERYENWMVTKE 216

  Fly   208 VNTLYNMITQPATDALIAER--FGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQ 270
            :|.   .|.:...|.:.:.|  .|..||...|::...|:..||.:.....|||.....:.:||:.
Worm   217 INI---GIHEKFDDEMKSYREFLGQDLPDWRELLSTASIFFINSNPFFDFPRPVLQKTVPIGGIS 278

  Fly   271 VGPIKPLPQHLL-----DLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRW 330
            |. :|.:.:..|     ::|:.....|: ||:||:|.|..:|...|:.|...|..:.:..|:.::
Worm   279 VN-LKWIKEQKLTKDWEEVLEMRKKTVL-ISFGSLVKSAYMPKKWRNGLLDVIKSMPDVTFIWKY 341

  Fly   331 KSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLN 395
            ::.:.......||::...|:||..||..|::..|::||||..|.|..:.|.|.:|.|.:.||..|
Worm   342 ETDDVSFADGVSNIHFSKWVPQTALLNDPRLSVFVTHGGLGSTMELAYSGKPAVVIPVFADQIRN 406

  Fly   396 SGAVKQRGFGVIVDFRDFDSNHITRG--LRIILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEH 458
            :..:.:....:.:.....::..:||.  ..::.|..:.:...:.:.....:|..|       .|:
Worm   407 ANMIARHRGVIYLHKNSMENVKVTRKAFTDVLFDDSYQKNAEKLANILMNQPYSP-------KEN 464

  Fly   459 VIKY-------GGAPHIQSEARHINWIVYNSIDV----LLFWLGILFLLIVALRKLIKIFKTAF 511
            ||||       |..|::....||:|:.....:|:    .||::.:..::||.:|.:.|..:..|
Worm   465 VIKYTEFLGEHGPFPNMDPHGRHLNYFQKTFLDIYTLFALFYIFVSTIIIVTIRFVYKFTRKHF 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	114/493 (23%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	102/451 (23%)
ugt-29	NP_001370778.1	GT1_Gtf-like	18..468	CDD:340817	106/457 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161393
Domainoid	1	1.000	172	1.000	Domainoid score	I2232
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790