DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-22

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_502633.1	Gene:	ugt-22 / 178330	WormBaseID:	WBGene00007455	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	548	Identity:	126/548 - (22%)
Similarity:	230/548 - (41%)	Gaps:	51/548 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLPLALL--AFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPL----- 60
            ||||.||  :|:...:|........||.|   ||......:...|.:.||::::  ..|:
Worm     7 LLPLLLLLGSFVGLTEPYKILMYTNLFGH---SHIKMLGAVSDTLTDAGHDLTV--LMPVIDFKQ 66

  Fly    61 -EKPVANYTDYVFQ---GMPLLTDIVDLSNFESE-W-----KPLGLPFKVPTYFMLHDWGLRSCK 115
             .|.....|..:.:   |..:...|..:..|.:: |     .||.:.|..|....:.   ...|:
Worm    67 ENKTAMKSTKNIIKIQPGQDISKTIETMEKFMTQLWTTDNSNPLFMVFHAPAMSAIF---ASQCR 128

  Fly   116 VALNSPLITQLLKSPIRYDVILLEHFSNDCMAAV-------AHLLNAPVIALSSCAIMPWHYKRM 173
            ..|....:.:.|::. .:|:.:.|.| :.|..|:       ||      :|:.||:.:....|.:
Worm   129 KVLEDKELIERLRAE-NFDLAITEPF-DTCAYALFEAIKIRAH------VAVLSCSRLDHVSKAI 185

  Fly   174 GSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEI 238
            |.|.....:|.....:.:.|::..|..|..||...:.|::.|..  .|..:|:...||:....|:
Worm   186 GQPIAPSYVPGTQSTHGERMTIWQRFMNILHFLMGDFLFSYIGD--EDFKVAKEIIPGVRSWREV 248

  Fly   239 VKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIK---PLPQHLLDLLD-RSPNGVIYISWGS 299
            :...|.:..|....:..|.|....:|.:||:.|...|   .||:....:|. |..|  |.:|:||
Worm   249 LPEASFIFTNHIPLMDFPAPTFDKIIPIGGISVKTQKKSLELPEKWNKILGLRKKN--ILVSFGS 311

  Fly   300 MVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAF 364
            ...|..:|...:..:.:....:.:..|:.::::.:........|:|..|||||.:||..|::..|
Worm   312 NARSADMPEHFKQNVLKVAESMPDVTFIWKYENEKDTLADHLDNVYLGDWLPQNELLGDPRLSLF 376

  Fly   365 ISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGL--RIILD 427
            ::||||...||....|.|.::.|.:.||..|:..:|:.|...::...|..:....|..  :::.:
Worm   377 VTHGGLASVTELALMGKPAVMVPLFADQARNANMLKRHGGAAVLHKTDLGNAETIRNTIKKVLEN 441

  Fly   428 KKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGI 492
            :|:.....|.:|....:|..|.......:|...|:|..|.:....||.::|.|..:|::...|.:
Worm   442 EKYRVNAERLAEMLNNQPTNPKDTLIKHVEFAAKFGQLPSMDPYGRHQSYIEYYLLDIISIALVL 506

  Fly   493 LFLLIVALRKLIK-IFKTAFCRGKISRD 519
            :........:||| .|:.....||:.:|
Worm   507 ILTTSFISFQLIKCTFRMCCGSGKVKKD 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	110/495 (22%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	97/450 (22%)
ugt-22	NP_502633.1	UDPGT	36..530	CDD:278624	112/510 (22%)
ugt-22	NP_502633.1	egt	<256..515	CDD:223071	62/260 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161379
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14115
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790