DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-45

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_500410.2	Gene:	ugt-45 / 177139	WormBaseID:	WBGene00021372	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	518	Identity:	125/518 - (24%)
Similarity:	236/518 - (45%)	Gaps:	55/518 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GKSHFDFFRPMFLALAERGHNISMYSYFPLEKPV-ANYTDYVFQGMPLLTDIVD----------- 83
            |.||......:...|.|.||:::.  ..|::.|: .|.|:.....:...||.::
Worm    28 GFSHMQTMGKLADILVEAGHDVTF--LMPVDVPIPQNGTELAKVVLVPTTDAINEIMGHAMKSGA 90

  Fly    84 LSNF--ESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLKSPIRYDVILLE--HFSND 144
            ::|.  .|.....|:.:...   |:......:.|..:::..:.|.:|.. ::|:.:.|  .||..
Worm    91 VANLWTHSANSKQGIMWSTD---MIGQVSYHNTKNLIDNKALVQQMKDE-KFDIGITELFDFSGL 151

  Fly   145 CMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLP----YTDEM-SLIDRLNNFFH 204
            ....|..|.|  |:...:.::........|:    ||:| :|:|    :||:. |::.||||.:.
Worm   152 AFFEVIGLKN--VMGAHTTSVFEGTLMATGA----PILP-SFVPASQTFTDDSGSILSRLNNLYM 209

  Fly   205 FHTVNTLYNMITQPATDALIAERFGPG-LPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGG 268
            .:......|.|...|..|| .|.:..| .|.|..:|.:.:...:|.......|:|...|::|:.|
Worm   210 TYWSYQFQNKIQSFAQKAL-DEHYEKGKAPKIWNLVSDITWFFVNSDPIFDFPKPLPQNIVEIAG 273

  Fly   269 LQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSL 333
            :.|..|||:.:...::|.:....|: :|:||:.:..|:|...:.::..:.:...:..|:.::...
Worm   274 ISVPEIKPVGKEWDEILSKRSKNVL-VSFGSIASPTTMPEAVKKSIVDAFAAFPDVTFIWKYDDT 337

  Fly   334 ESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGA 398
            ||.......|::...|:||.|||...:|..|.:|||:....|:....||::|.|.:|||..|:..
Worm   338 ESKLTAHLDNVHIVKWMPQNDLLADKRISMFWTHGGMGSLMESAQKSVPLVVVPIFGDQMRNAQI 402

  Fly   399 VKQRGFGVIVDFRDF-DSNHITRGLRIILD----KKFAERVRR--SSEAF--RQRPIPPIKLATW 454
            .|:.|..:|.|..|. ::..:...|:.:|:    ||.||.:.|  ::|.|  ||:.|..:::|.
Worm   403 AKRHGVALIYDKMDLSNTKKLIGALKEVLENPEYKKSAELLARILATERFSPRQKIIDTVEMAG- 466

  Fly   455 WIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIK--IFKTAFCRGK 515
                  ::|..|...|..:..:::.|.::|:::..:.|.||.||:...||:  :.|..|...|
Worm   467 ------RFGQMPRWTSAGKEFSFLKYFNLDLVIIAVFIFFLSIVSTVLLIRHLLAKLGFSGDK 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	115/486 (24%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	107/453 (24%)
ugt-45	NP_500410.2	egt	14..513	CDD:223071	122/506 (24%)
ugt-45	NP_500410.2	UDPGT	19..510	CDD:278624	120/503 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14613
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860