DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-60

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001021158.1	Gene:	ugt-60 / 176366	WormBaseID:	WBGene00007402	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	535	Identity:	121/535 - (22%)
Similarity:	227/535 - (42%)	Gaps:	98/535 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DAAHILGLFQHPG--KSHFDFFRPMFLALAERGHNISMYSYF----------PLEKPVANY---- 67
            |:..||.:.  ||  .||..|...:...|...||::.|::..          .|.:.|:.|
Worm    14 DSLRILQIV--PGFTNSHVLFNYRLAETLRFLGHDVKMWTQMEMAMLDTGNNKLPEGVSEYRIPI 76

  Fly    68 --TD-------YVFQGMPLLTDIVDLSNFESE------WKPLGLPFKVPTYFMLHDWGLRSCKVA 117
              ||       .|||.|          .|||.      |  .|..||        |..:.:|:..
Worm    77 HFTDTLKTEGLKVFQSM----------MFESGDAHDLWW--TGQEFK--------DMRVEACEQM 121

  Fly   118 LNSPLITQLLKSPIRYD--VILLEHFSNDCMAAVAHLLNAP-VIALS-SCAIMPWHYKRMG---- 174
            |..   .:.:....|.|  .:.:.||.:.|..|:|..:|.. ||.:: ..:|..:...::|
Worm   122 LRH---DESVYEDFRKDGFDVAIAHFHDLCPLAIAKKMNVKRVIWITHGTSIYEFSAVQLGLRTI 183

  Fly   175 -SPFINPIMPMNFLPYTDEMSLIDRL-NNFFHFHT---VNTLYNMITQPATDALIAERFGPGLPP 234
             |...:|:....|     ....:||: |..:|...   ||...|::..  .:....|..|.....
Worm   184 PSTIPHPLSSAGF-----SQLFLDRVQNTLWHLSLLDFVNLPQNLLVD--ENLFYREFVGADQDD 241

  Fly   235 INEIVKNT-SLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPL--PQHLLDLLDRSPNGVIYIS 296
            :.::.|.| ..:|||....|..|||...::...|.|.|...|.|  .:.|.|::::..:|:|..|
Worm   242 LWDLAKTTVPSLLINGDRMLDFPRPLPIHIAFSGELGVSKGKKLVMEKWLEDIIEKPSDGLIVFS 306

  Fly   297 WGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRW-KSLESLEDKQPSNLYTFDWLPQRDLLCHPK 360
            .|::.|:..:|:...::...:..:||.|..:.|. ||:...|..:  ||:...||||:|::.|||
Worm   307 LGTVSNTTNMPAQMINSFLGAFGKLKTYTILWRMEKSVAGAEKYE--NLHLVKWLPQKDIMRHPK 369

  Fly   361 IRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRII 425
            ::..|:|||.....||...|:|.::.|.:.||.:|:...::.|...::|..|...|::...::..
Worm   370 MKLMIAHGGYNSFLEAAQAGIPAVLMPLFADQKINAKRAQRYGMATVLDKLDLTINNVYGAIKEA 434

  Fly   426 LDKKFAERVRR----SSEAFRQRPIPPIKLATWWIEHVIKYGGAPH---IQSEARHINWIVYNSI 483
            |..:::...::    .|:...::|...::       :.:|...:|.   ...:::|::::.::::
Worm   435 LKPEYSTNAKKLSAMLSDQVARKPYSALR-------YSLKLATSPKPSLFTLKSQHLSFLEFHNL 492

  Fly   484 DVLLFWLGILFLLIV 498
            |:  |.:.:|...||
Worm   493 DI--FSIVLLTAFIV 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	117/522 (22%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	105/472 (22%)
ugt-60	NP_001021158.1	Glycosyltransferase_GTB_type	17..>161	CDD:299143	38/168 (23%)
ugt-60	NP_001021158.1	egt	<253..464	CDD:223071	56/219 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910