DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt-58

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_496059.2	Gene:	ugt-58 / 174507	WormBaseID:	WBGene00009450	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	499	Identity:	124/499 - (24%)
Similarity:	212/499 - (42%)	Gaps:	62/499 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LAERGHNISMYSYFPLEKPVANYTDYVFQGMP------LLTDIVDLSNFESE---WKPLGLPFKV 100
            ||||||.::.....|....:..:.....:..|      .|.:|....|..|.   |.
Worm    41 LAERGHKVTWLEIGPERSDIVLHQQVSREFWPAQFGDRTLQEIYQFKNHTSHSELWN-------- 97

  Fly   101 PTYFMLHD----W--GLRSCKVALNSPLITQLLKSPIRYDVILLEHFS--------NDCMAAVAH 151
            |.|...::    |  .:|.|...|:        :|..::|.::.:.||        |.|...:|.
Worm    98 PQYTNENEQTTGWLASIRLCDSVLS--------RSKSKFDKMVEKQFSTVIVDDLYNSCGVLMAG 154

  Fly   152 LLNAPVIALSSCAIMPWHYKRMGSPFINPI-MPMNFLP-----YTDEMSLIDRLNNFFHFHTVNT 210
            |..:..|..|...:      |..|.:.|.. .|.::||     .||:::...||.|...:.....
Worm   155 LKKSVYIYWSMTGL------RTESAWANQSPSPPSYLPVAGTGLTDDLTFSQRLYNVASYFKQLY 213

  Fly   211 LYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIK 275
            ::..|.||..|| :.:::.||:....||.:|.|:..:|........|||.|.|..:|.:|....|
Worm   214 IHQHIVQPRIDA-VFQKYYPGVESTFEIERNASINFVNTPPIFDFSRPYMPRVNFIGAIQCRKPK 277

  Fly   276 PLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQ 340
            .||:.....:...|:|.:.:|.|..|..|..|...|.|...:...|....|:  |::........
Worm   278 ELPKEFTSWISAYPDGFVVLSTGFTVQWNKSPEHIRQAYLDTFKYLPNLLFI--WQTGLPNSSNL 340

  Fly   341 PSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFG 405
            ||||....|||.:|||.|.|.|..:|||||....|:::.|||::..|.....:.|...:..|..|
Worm   341 PSNLLVKPWLPLQDLLGHQKCRCHVSHGGLNSVIESVYHGVPVVGVPLTSRGYDNLLRITARDSG 405

  Fly   406 VIVDFRDFDSNHITRGLRIILDKKFAERVRRSSEAFRQR----PIPPIKLATWWIEHVIKYGGAP 466
            |:|:..:|....:|..:..:::.   |:.::....|:..    |...:..|.:|:|.:.::...|
Worm   406 VMVEKSEFSGEILTAAINEVIEN---EKYKKEMLIFQDMVIDVPYTELYHAAFWVEFIERHQEVP 467

  Fly   467 HIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIK-IFKT 509
            |.:|.|.|:|::.|..:||:.|:..::|..:..:...|: :|:|
Worm   468 HARSGADHLNFLQYFLVDVIAFFFFVIFCTLSIIYYTIRTVFRT 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	119/474 (25%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	110/448 (25%)
ugt-58	NP_496059.2	UDPGT	17..485	CDD:278624	117/471 (25%)
ugt-58	NP_496059.2	Glycosyltransferase_GTB_type	<200..462	CDD:299143	73/267 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14290
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810