Protein Alignment Ugt36F1 and UGT3A1

DIOPT Version :10

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_047272663.1
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 526
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 144/540 - (26%)
• Similarity: 226/540 - (41%)
• Gaps: 113/540 - (20%)

  Fly    33 SHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVFQGMPLLTDIVDLSNFESEWKPLGLP 97
            ||:.....:...|.|.|||::|...               .|..|:.||      :.|.|    .
Human    37 SHYLLLDRVSQILQEHGHNVTMLHQ---------------SGKFLIPDI------KEEEK----S 76

  Fly    98 FKVPTYFMLHDWGLR-------------------------------SCKVALNSPLITQLLKSPI 131
            ::|..:|...|...|                               .|...|:...|...||:.
Human    77 YQVIRWFSPEDHQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQCSYLLSRKDIMDSLKNE- 140

  Fly   132 RYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRM--GSPFINPIMPMNFLP-----Y 189
            .||::.:|.| :.|...:|..|..|.:     ||:|..:..:  |.|     .|::::|     .
Human   141 NYDLVFVEAF-DFCSFLIAEKLVKPFV-----AILPTTFGSLDFGLP-----SPLSYVPVFPSLL 194

  Fly   190 TDEMSLIDRLNNFFHFHTVN-TLYNMITQPATDALIAERFGPGLPPI-NEIVKNTSLMLINQHYA 252
            ||.|....|:.||..|.:.: :.::|  |...|..|.|.|..|..|: :.::....|..:|..:|
Human   195 TDHMDFWGRVKNFLMFFSFSRSQWDM--QSTFDNTIKEHFPEGSRPVLSHLLLKAELWFVNSDFA 257

  Fly   253 LTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLL-DRSPNGVIYISWGSMVNSNTLPSGKRSALFQ 316
            ....||..||.:.:|||...||||:||.|.:.: :....|.:.:::|||:|::           |
Human   258 FDFARPLLPNTVYIGGLMEKPIKPVPQDLDNFIANFGDAGFVLVAFGSMLNTH-----------Q 311

  Fly   317 SISQLKEYNFVMR-------WKSLESLEDKQ---PSNLYTFDWLPQRDLLCHPKIRAFISHGGLL 371
            |...||:.:....       |....|...:.   .:|:...|||||.|||.||.||.|::|||..
Human   312 SQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAHPSIRLFVTHGGQN 376

  Fly   372 GTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVR 435
            ...|||..||||:..|..|||..|...|..:.:||.:......::.:|..:: :|.||::...|.
Human   377 SVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTLTLTMKQVIEDKRYKSAVV 441

  Fly   436 RSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGIL------- 493
            .:|.....:|:.|.:....||:|:::.|||.|::..|....|.....|||.:|.||:.
Human   442 AASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPWHEQYLIDVFVFLLGLTLGTMWLC 506

  Fly   494 --FLLIVA--LRKLIKIFKT 509
              .|.:||  ||...|:.||
Human   507 GKLLGVVARWLRGARKVKKT 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	GT1_Gtf-like	21..448	CDD:340817	120/466 (26%)
UGT3A1	XP_047272663.1	Glycosyltransferase_GTB-type	36..526	CDD:471961	142/538 (26%)