Protein Alignment Ugt36F1 and UGT3A1

DIOPT Version :9

• Sequence 1: NP_609909.1
• Gene: Ugt36F1 / 35137
• FlyBaseID: FBgn0027074
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_689617.3
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 523
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 155/568 - (27%)
• Similarity: 241/568 - (42%)
• Gaps: 115/568 - (20%)

  Fly     6 LALLAFLLR-PKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTD 69
            |.|:||||. ...::||.||.: ...|.||:.....:...|.|.|||::|...
Human     7 LLLVAFLLSGVLLSEAAKILTI-STLGGSHYLLLDRVSQILQEHGHNVTMLHQ------------ 58

  Fly    70 YVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLR---------------------- 112
               .|..|:.||      :.|.|    .::|..:|...|...|
Human    59 ---SGKFLIPDI------KEEEK----SYQVIRWFSPEDHQKRIKKHFDSYIETALDGRKESEAL 110

  Fly   113 ---------SCKVALNSPLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPW 168
                     .|...|:...|...||:. .||::.:|.| :.|...:|..|..|.:     ||:|.
Human   111 VKLMEIFGTQCSYLLSRKDIMDSLKNE-NYDLVFVEAF-DFCSFLIAEKLVKPFV-----AILPT 168

  Fly   169 HYKRM--GSPFINPIMPMNFLP-----YTDEMSLIDRLNNFFHFHTVN-TLYNMITQPATDALIA 225
            .:..:  |.|     .|::::|     .||.|....|:.||..|.:.: :.::|  |...|..|.
Human   169 TFGSLDFGLP-----SPLSYVPVFPSLLTDHMDFWGRVKNFLMFFSFSRSQWDM--QSTFDNTIK 226

  Fly   226 ERFGPGLPPI-NEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLL-DRS 288
            |.|..|..|: :.::....|..:|..:|....||..||.:.:|||...||||:||.|.:.: :..
Human   227 EHFPEGSRPVLSHLLLKAELWFVNSDFAFDFARPLLPNTVYIGGLMEKPIKPVPQDLDNFIANFG 291

  Fly   289 PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMR-------WKSLESLEDKQ---PSN 343
            ..|.:.:::|||:|::           ||...||:.:....       |....|...:.   .:|
Human   292 DAGFVLVAFGSMLNTH-----------QSQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATN 345

  Fly   344 LYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIV 408
            :...|||||.|||.||.||.|::|||.....|||..||||:..|..|||..|...|..:.:||.:
Human   346 VKIVDWLPQSDLLAHPSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSI 410

  Fly   409 DFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEA 472
            ......::.:|..:: :|.||::...|..:|.....:|:.|.:....||:|:::.|||.|::..|
Human   411 RLNQVTADTLTLTMKQVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYA 475

  Fly   473 RHINWIVYNSIDVLLFWLGIL---------FLLIVA--LRKLIKIFKT 509
            ....|.....|||.:|.||:.         .|.:||  ||...|:.||
Human   476 FQQPWHEQYLIDVFVFLLGLTLGTMWLCGKLLGVVARWLRGARKVKKT 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	138/519 (27%)
		YjiC	38..461	CDD:224732	122/474 (26%)
UGT3A1	NP_689617.3	UDPGT	23..523	CDD:330975	146/550 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150059
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740