DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and AgaP_AGAP007920

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_317561.4	Gene:	AgaP_AGAP007920 / 1278034	VectorBaseID:	AGAP007920	Length:	1023	Species:	Anopheles gambiae

Alignment Length:	497	Identity:	209/497 - (42%)
Similarity:	316/497 - (63%)	Gaps:	8/497 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANY 67
            :|...:|..|...:..:|..:||||.|||:|||.||:|:...|||.||.:::.|:||.:.|.|||
Mosquito     8 MLRTVILVALALSQGTEAYKVLGLFPHPGQSHFHFFQPVLKGLAEAGHEVTVVSHFPEKNPPANY 72

  Fly    68 TDYVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLKSPIR 132
            .|....||..|:|.|....|  |::|....|.  .:|||:.||..:|..||||..|..:|.|.::
Mosquito    73 HDLPLAGMTSLSDSVSFELF--EYRPGFGHFM--EFFMLYTWGKEACANALNSTAIQTVLDSKVQ 133

  Fly   133 YDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTDEMSLID 197
            ||:||:|.|::|||..:||.|.||.|.||||.:|||||:|:|:|.:...:|..|:.||:.|....
Mosquito   134 YDLILVEQFNSDCMLGIAHQLKAPYIGLSSCPLMPWHYERVGNPTLPAYIPALFMGYTERMDFSQ 198

  Fly   198 RLNNFFHFHTVNTLYNMITQPATDALIAERFGPG-LPPINEIVKNTSLMLINQHYALTGPRPYAP 261
            ||.|:....:...||:.....|.:.|:.||||.| :|.:.|:.:.|::|.:||||:|:|.:|.:|
Mosquito   199 RLANWITVQSFKALYSWFNDAAANKLLGERFGQGAIPDVRELQQRTAMMFVNQHYSLSGAKPLSP 263

  Fly   262 NVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNF 326
            .|:|:||:.:...:||...|..|||.:.:||||||||||:.:.|||:.||.|:.:::.:.|: ..
Mosquito   264 AVLEIGGIHIRDFRPLEADLQQLLDTADHGVIYISWGSMIRAETLPAEKRDAILKALGRFKQ-RV 327

  Fly   327 VMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGD 391
            :.:|:: |:|.: ||||::...|||||::|||||:|.|:|||||||::||.:||||::.||.|||
Mosquito   328 IWKWEN-ETLPN-QPSNVHIRKWLPQREILCHPKVRVFMSHGGLLGSSEAAYCGVPVVATPMYGD 390

  Fly   392 QFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDKKFAERVRRSSEAFRQRPIPPIKLATWWI 456
            |:.|:.|:..||.||::.:.|..::.:...||.:|:.:..|..::.|.::|.||..|::.|.||.
Mosquito   391 QYNNAAALANRGMGVVLAYEDITADSVYDALRKVLEPEAMEHAKQVSFSYRNRPQSPLESAVWWC 455

  Fly   457 EHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIV 498
            |||...||.|..||.:..:.|..|:..||.:..:..|.||||
Mosquito   456 EHVAATGGLPLAQSYSSELPWYSYHQFDVYIVTITFLILLIV 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	201/468 (43%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	180/423 (43%)
AgaP_AGAP007920	XP_317561.4	egt	6..493	CDD:223071	204/491 (42%)
		UDPGT	27..508	CDD:278624	205/478 (43%)
		egt	488..976	CDD:223071	5/10 (50%)
		UDPGT	518..980	CDD:278624
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BKDN
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100631at6960
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
TreeFam	1	0.960	-	-
	6	5.780