DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and AgaP_AGAP002327

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_312644.5	Gene:	AgaP_AGAP002327 / 1273643	VectorBaseID:	AGAP002327	Length:	552	Species:	Anopheles gambiae

Alignment Length:	526	Identity:	137/526 - (26%)
Similarity:	228/526 - (43%)	Gaps:	64/526 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 AAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVFQG-----MPLLT 79
            |.:||.|...|.|||..:.|.:|..|.|.|||:::.| |..|..|...|..|..|     |....
Mosquito    32 AENILFLQTTPSKSHHIWNRQIFDRLYENGHNLTILS-FEQETSVPGKTFLVMDGYYAKMMAAFA 95

  Fly    80 DIV-DLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVAL----NSPLITQLLKSP--IRYDVIL 137
            |.. |.|::|..:   |....|..|:          |||.    ....|.:||..|  .|:|:::
Mosquito    96 DSAGDFSSYEHAF---GNIMNVYQYY----------KVASGLLEEEDAIQRLLAYPRTFRFDLVI 147

  Fly   138 ------------LEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYT 190
                        ||||.           |.|::::|...|..:.......|.....:|.....:.
Mosquito   148 HDFTMGQWLLGFLEHFH-----------NPPLVSISPYNIPSYTQYLADVPVYTTYLPHPASSFG 201

  Fly   191 DEMSLIDRLNNFFHFHTVNTLY-NMITQPATDALIAERF-GPGLPPINEIVKNTSLMLINQHYAL 253
            ..|:.::|:.|..:: ..:.|| ..:..|.....:...| |.....:..:.:.:.|:|:|...||
Mosquito   202 TRMTFVERVQNTLYW-WFDMLYRQQVYMPQEQQRLVRVFEGANRTHVKLLERRSELVLVNSDPAL 265

  Fly   254 TGPRPYAPNVIEVGGLQVGPIKPLPQHLLD--LLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQ 316
            ...:...|||::||||.:...:.:|...|:  .:.|:..||:..|:|:.|.|..|.:.....|.:
Mosquito   266 DFYQLLPPNVVQVGGLHIKRAEEMPPVSLEGQFIARANKGVVLFSFGTNVQSEMLGAEVNRQLLE 330

  Fly   317 SISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGV 381
            ..:.:.:|.|:  ||...:.....|.|:....|:||..:|.:.:.:..:||||||...||...||
Mosquito   331 LFASMPDYGFI--WKHANADGLIMPPNVLMAPWVPQSAVLANGRTKLLVSHGGLLSLQEAAWNGV 393

  Fly   382 PMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGL-RIILDKKFAERVRRSSEAFRQRP 445
            |::..||:.|||.|...::..|.|:.:.....::..:...: :|:.|..:..|.:..|..||.:|
Mosquito   394 PVIGVPFFADQFSNVRRIELAGIGIGIPSTQLNAVTLKEAMDKILSDSSYRARSKELSYRFRTQP 458

  Fly   446 IPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSID----VLLFWLGILFLLIVALRKLIKI 506
            .||::.|.:|||..|...|..:::|..|.:.......:|    |||..||...:..:.||..|::
Mosquito   459 EPPLERAIFWIEKTIANKGLRYLRSPTRSMAPYQVYGLDMVGVVLLIALGYYLIFKLLLRCCIQL 523

  Fly   507 FKTAFC 512
               .||
Mosquito   524 ---VFC 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	128/499 (26%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	114/451 (25%)
AgaP_AGAP002327	XP_312644.5	egt	19..494	CDD:223071	126/489 (26%)
AgaP_AGAP002327	XP_312644.5	UDPGT	45..524	CDD:278624	129/509 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
TreeFam	0	0.000	Not matched by this tool.
	3	2.910