DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and AgaP_AGAP002449

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_312497.5	Gene:	AgaP_AGAP002449 / 1273514	VectorBaseID:	AGAP002449	Length:	533	Species:	Anopheles gambiae

Alignment Length:	520	Identity:	144/520 - (27%)
Similarity:	248/520 - (47%)	Gaps:	41/520 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYT 68
            |.:.|||.||.......|.||.:.....|||...|..:...|..|||||:..:.||        .
Mosquito    25 LRILLLAGLLAASCCSGADILMITMGGTKSHKIPFLELAKGLIPRGHNITFLNGFP--------A 81

  Fly    69 DYVFQGMPLLT--DIVDLSNFESEWKPLG------LPFKVPTYFMLHDWGLRSCKVALNSPLITQ 125
            |:...|:..:|  .:|:.....:.|..||      :|..:...|.. .|.:  |...|.......
Mosquito    82 DFTLHGLQEVTPSGLVEYIRNYTNWDLLGARMRGDMPLSLWDVFRF-SWQI--CDATLEDKETMD 143

  Fly   126 LLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYT 190
            ||..  ::|:::|:....:|...:.:.|..|.:.:::...........|:|......|..:.|.|
Mosquito   144 LLGR--KFDLMILDGAFPECALGLVYRLGVPFMYINTVGFYTGTMALAGNPVPYSTTPAFYRPVT 206

  Fly   191 DEMSLIDRLNNFFH------FHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQ 249
            |:|...:||:|.|:      .:|.:.||       ...::....|..:|.|..:.:|.|.:|.|.
Mosquito   207 DDMRFFERLSNAFYTLVGDVVYTPSMLY-------LQHMVRRHLGSDVPNIWNLSRNVSFILQNG 264

  Fly   250 HYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLL-DRSPNGVIYISWGSMVNSNTLPSGKRSA 313
            ..::|.|||..|||.|:..:...|..|||:.|.|.: ....:|.||:|.||.|.:..:|...|..
Mosquito   265 QASVTYPRPLLPNVAEIACIHCKPAAPLPKDLEDFIAGAGESGFIYVSMGSSVKAANMPDHLRQL 329

  Fly   314 LFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIH 378
            |.|:.::| .|..:.::::..:|....|:|:....||||:|:|.|.|:|||::|||||...|.::
Mosquito   330 LVQAFARL-PYRVLWKYEASPALLTDLPANVKIGRWLPQQDILGHRKLRAFVTHGGLLSMFETVY 393

  Fly   379 CGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGL-RIILDKKFAERVRRSSEAFR 442
            .|||::..|.:.|...|:......|:.:.:|.....|..:.|.: ::|.|..:....:|.....:
Mosquito   394 HGVPVVTMPVFCDHDANAAKAVADGYALKLDLETITSERLVRAIHKVIHDPTYRREAKRRQVLLK 458

  Fly   443 QRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIF 507
            .:...|::.|.:|.|:||::.||.|:||.||::|::.|..:|.:||.:|:::|    ||.|.:::
Mosquito   459 DQRSTPLETAIYWTEYVIRHNGAYHLQSPARNLNFLQYYCLDQVLFLIGVVYL----LRALTRLY 519

Fly 508 507
Mosquito 520 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	131/483 (27%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	114/438 (26%)
AgaP_AGAP002449	XP_312497.5	UDPGT	44..509	CDD:278624	133/485 (27%)
		Glycosyltransferase_GTB_type	45..>76	CDD:299143	11/30 (37%)
		egt	<238..497	CDD:223071	81/259 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
TreeFam	0	0.000	Not matched by this tool.
	3	2.910