DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and AgaP_AGAP002783

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_312138.5	Gene:	AgaP_AGAP002783 / 1273185	VectorBaseID:	AGAP002783	Length:	536	Species:	Anopheles gambiae

Alignment Length:	527	Identity:	137/527 - (25%)
Similarity:	243/527 - (46%)	Gaps:	88/527 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPL---EKPVANYTDYVFQGMPLLTD 80
            :||.||.:|..|.|.|...:||:..|||.|||.|.:.:..||   ::|  |.|..:.|
Mosquito    23 EAAKILAIFPVPLKQHQLVYRPLIEALAGRGHEIVLVTTDPLDMADRP--NGTRSIEQ------- 78

  Fly    81 IVDLSNFESEWKPLGLPFKVPTYFMLHDWGL-------------RSCKVA-LNSPLITQLLKSP- 130
             :|||          ..:::|....|...||             |:...| |..|.:.:|::|.
Mosquito    79 -IDLS----------FAYQLPALAQLGWVGLDGRDMLRNIFDVMRTISAAELRHPAMQKLIESAN 132

  Fly   131 ----------IRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPI-MPM 184
                      .|:||:::|......|.|.|....||::.:::.......::.:|:| .:|| .|.
Mosquito   133 LQDGTGGTKCNRFDVVMVEWSGVTLMNAFAEHFRAPLVGIANGGAYINAHEALGNP-NHPIGYPS 196

  Fly   185 NFLPYTDEMSLIDRLNNF-------FHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNT 242
            .|:|:::::||:.|:::.       |:::|...       ||.:.:....||..:..:.:|.:|.
Mosquito   197 IFMPFSEDLSLLQRISSVLFTVWYRFYYYTEEI-------PAQNLIAKSSFGEHISDLRQIEQNA 254

  Fly   243 SLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLP 307
            .|:|||.:..|...||..|..:.:||:.......||:.|...|.:|...|:|:   ::|.|....
Mosquito   255 DLLLINAYQQLGNVRPVGPTTVYLGGIHQQHRHQLPEDLFLFLAQSDEPVVYV---NLVASLGGV 316

  Fly   308 SGKRSALFQSISQ-LKEYNFVMRWKSLESLEDKQPSN----LYTFDWLPQRDLLCHPKIRAFISH 367
            :|:  |....|:: |...:....|...||::   |.|    :|....:||..:|.|.|:|||::.
Mosquito   317 AGQ--ARIDKIAKALAHLDLASVWALDESMD---PINSTGRIYQSHSVPQEAVLGHSKVRAFLTD 376

  Fly   368 GGLLGTTEAIHCGVPMLVTPF---YGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDK 428
            ||.:...:||...||::...:   | |.:|......:.|   |:...||::......|: :::::
Mosquito   377 GGQINVEDAIQHKVPVVGISYSTSY-DHYLRQIVKYEAG---IISLIDFETQTFVDKLQDVLINE 437

  Fly   429 KFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGIL 493
            ::.|.|.:.......:|...::.|.||||:|.:.||...:  ..||::|..|..:|||:. :|:|
Mosquito   438 RYQENVNKLHRLLNDQPQTALERAVWWIEYVARNGGTRPL--HVRHLSWFEYLMLDVLIV-VGVL 499

  Fly   494 FLLIVAL 500
            ..|..||
Mosquito   500 ASLACAL 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	131/512 (26%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	115/467 (25%)
AgaP_AGAP002783	XP_312138.5	egt	17..494	CDD:223071	131/512 (26%)
AgaP_AGAP002783	XP_312138.5	UDPGT	25..517	CDD:278624	136/525 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27372
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
TreeFam	0	0.000	Not matched by this tool.
	5	5.020