DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and AgaP_AGAP007028

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_308744.4	Gene:	AgaP_AGAP007028 / 1270077	VectorBaseID:	AGAP007028	Length:	539	Species:	Anopheles gambiae

Alignment Length:	520	Identity:	162/520 - (31%)
Similarity:	272/520 - (52%)	Gaps:	27/520 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLPLALLAFLL--RPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPL-EKPV 64
            |..:.||..||  ...|:..|.|||:....|:||:.....:..||.:.||.:::.|.:|: :.|.
Mosquito     7 LSAVVLLGLLLLGSAPPSQGARILGILPSVGRSHYIIGAGLMKALLDAGHEVTIVSPYPMKDAPA 71

  Fly    65 ANYTDYVFQGMPLLTDIV--------DLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSP 121
            ..:.|.      ||.|:.        ||..::|      .|..:..|.:..:.|.::.:..|..|
Mosquito    72 GLHRDI------LLPDLATSHGVSGPDLFQYKS------APNLMVLYLVYSEIGPQASEALLQHP 124

  Fly   122 LITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNF 186
            .:.:|::|..|:|.:::|.|:::.:..:|......:...|......|..:.:|:|:....:|..|
Mosquito   125 KMVELMQSGERFDAVIVESFASEVLYGLAEHFGGQLFVFSPFGASMWTNELVGTPYPYSYIPHTF 189

  Fly   187 LPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHY 251
            |.||:|||...|..|....|.....|..:..|..:|:....|........:.:::..|..:|||:
Mosquito   190 LSYTNEMSFWQRFTNALVGHADKLYYRCVFLPQQEAMYRRFFPNAKLTFQQTLESVRLAFVNQHF 254

  Fly   252 ALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQ 316
            .|:.|.|||||::|:||:|:.|.|.||..:...:|.:|:||||.|.|||:.....|..||:|...
Mosquito   255 TLSYPHPYAPNMVEIGGIQIQPAKKLPADIQKYIDEAPHGVIYFSMGSMLKGRNFPEDKRAAFVN 319

  Fly   317 SISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGV 381
            ....||| |.:.:::: :||.|| |.|:....|:||.|:|.|||::.||:|||||||||.::.|.
Mosquito   320 VFRGLKE-NVIWKYEN-DSLPDK-PPNVLIKAWMPQSDILAHPKVKLFITHGGLLGTTEGLYHGK 381

  Fly   382 PMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILD-KKFAERVRRSSEAFRQRP 445
            ||:..|.||||.||....:|.|:||.:|:.......|...:|.:|| ..:.||.|..|:.:|.:|
Mosquito   382 PMVGIPIYGDQELNLARAEQAGYGVKLDYDTLSEETIAAAIRTVLDGPAYGERARLISDRYRDQP 446

  Fly   446 IPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTA 510
            :.|.|.|.:|:|:|:::.|||.:||.:..::::.||.:||......|...:::....:::...|:
Mosquito   447 LGPAKAAVYWVEYVLRHKGAPQLQSPSVRLSFVQYNLLDVYAVMGAIALSVLIGAGLMLRALLTS 511

Fly 511 510
Mosquito 512 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	154/477 (32%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	138/432 (32%)
AgaP_AGAP007028	XP_308744.4	egt	24..465	CDD:223071	145/455 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27372
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
TreeFam	0	0.000	Not matched by this tool.
	5	5.020