DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and AgaP_AGAP007029

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_308743.3	Gene:	AgaP_AGAP007029 / 1270076	VectorBaseID:	AGAP007029	Length:	522	Species:	Anopheles gambiae

Alignment Length:	536	Identity:	178/536 - (33%)
Similarity:	295/536 - (55%)	Gaps:	49/536 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LALLAFLLRPK-PNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTD 69
            :||||.|...| |.:.|.||.:|....:||:.....:...||.|||.:|:.:.||.:||:.||.|
Mosquito     9 VALLAALYAAKTPVEGAKILAVFPTSSRSHYIVGSALMKELARRGHEVSVINPFPQKKPLKNYRD 73

  Fly    70 YVFQGM-PLLTDIVDLSNFE----SEWKPLGLPFK----VPTYFMLHDWGLRSCKVALNSPLITQ 125
            ....|. .|:.|:|. :.||    |.|:.:.:.:|    :..|.::|             |.:.:
Mosquito    74 IDVSGSEELVKDLVP-NMFEMADQSVWESITMTYKFGQMLANYTLMH-------------PNVAK 124

  Fly   126 LLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYT 190
            |:||..::|:|::|.|.||.....||...||.:|||:.....|....:|:|.....:|..||.:|
Mosquito   125 LIKSNEKFDLIIMESFLNDAHLGFAHHFKAPCVALSTFGASRWTNDMVGTPSPLSYVPHPFLSFT 189

  Fly   191 DEMSLIDRLNNFFHFHTVNTLYN-----MITQPATDALIAERFGPGLPPINEIVKN-TSLMLINQ 249
            |.||.:.|:.|     |:.||.:     ::..|...|:....|....||:.|:.:: .||:|:|.
Mosquito   190 DRMSFVQRIGN-----TLMTLMDTVLGQVLDLPVQSAMYEAAFPDPKPPLEELRRHAVSLVLLNN 249

  Fly   250 HYALTGPRPYAPNVIEVGGLQVG--PIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRS 312
            |::|:.||||.||::||||:.|.  | .|||:.:..:||.:.:||||.|.||.:.|:.||..||.
Mosquito   250 HFSLSYPRPYVPNMVEVGGMHVNRKP-NPLPEDIQRVLDGAEHGVIYFSMGSNIQSSQLPVAKRE 313

  Fly   313 ALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAI 377
            |:.:..|:||:   .:.||..:.....:|:|:....|.||.|:|.||.:|.||:|||||.|||::
Mosquito   314 AILRVFSRLKQ---TVLWKWEDETLPNRPANVIVKAWWPQDDVLAHPNVRLFITHGGLLSTTESL 375

  Fly   378 HCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGL-RIILDKKFAERVRRSSEAF 441
            :.|||::..|.:|||:||....::.|:|:::.::|.....:...: ||:.:..|....:..|..:
Mosquito   376 YHGVPVIGIPVFGDQYLNMAKAERTGYGLLLPYQDISEERLAHAIDRILREPSFKTVAQSISARY 440

  Fly   442 RQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKI 506
            |.:|..|::||.:|:|:||::|||.|::|..:.:.::.|:.:|||:..:|...|.:..|.||:
Mosquito   441 RDQPQEPLELAAFWVEYVIRHGGAEHLKSAGQELGFLQYHGVDVLVTIVGGPILFVYLLSKLL-- 503

  Fly   507 FKTAFCRGKISRDTKT 522
                 |.|:..::..|
Mosquito   504 -----CGGRSKKNAST 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	162/485 (33%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	147/440 (33%)
AgaP_AGAP007029	XP_308743.3	egt	20..489	CDD:223071	164/491 (33%)
AgaP_AGAP007029	XP_308743.3	UDPGT	25..497	CDD:278624	165/494 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27372
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
TreeFam	0	0.000	Not matched by this tool.
	5	5.020