DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt5b2

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001170970.2	Gene:	ugt5b2 / 100415799	ZFINID:	ZDB-GENE-100406-4	Length:	531	Species:	Danio rerio

Alignment Length:	523	Identity:	151/523 - (28%)
Similarity:	248/523 - (47%)	Gaps:	62/523 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SHFDFFRPMFLALAERGHNISM---------------YSYFPLEKPVANYTDYVFQGMPLLTDIV 82
            ||:.....:..||:.:||::::               |:...| |....|...|.:  ...:.|:
Zfish    37 SHWVNMNILVEALSAKGHDVTVMRTASSCYIKEFSPHYTSINL-KSKGGYNKEVLE--QFASRIM 98

  Fly    83 DLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLKS--PIRYDVILLE--HFSN 143
            .:....|.|..|.|...:...|:......|  ::.:|.....||::|  ..:||:||.:  .|..
Zfish    99 HILRDGSTWGHLKLQADMWQSFLKIFEAER--EMIVNMIEDQQLMQSLKDAKYDLILTDPNMFGG 161

  Fly   144 DCMAAVAHLLNAPVIALSSCAIMPW------HYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNNF 202
               ..:.|.|..|::     ..:.|      |:....||.  ..:||..|..:|.||.:.|:.|.
Zfish   162 ---VILGHYLKLPMV-----YNVRWAGYNEAHFSIAPSPL--SYVPMPSLELSDRMSFLQRVYNV 216

  Fly   203 FHFHTVNTLYNMITQPATDALIAERF-GPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEV 266
            ..:..:.....::..|..||| |||| |||...:: :|:...|.|....:....|||..||||.:
Zfish   217 VMYIFIEIGAALVISPINDAL-AERFIGPGTSFLS-LVQGADLWLHRVDFVFEYPRPTMPNVIYM 279

  Fly   267 GGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRW 330
            .|.|..|.|||||.|.|.:..| .:|||.:|.|::::.  ||.....|:.::.::|.: ..:.|:
Zfish   280 AGFQCKPSKPLPQDLEDFVQSSGDHGVIIMSLGTLIDK--LPDDVAEAIAEAFAELPQ-KIIWRY 341

  Fly   331 KSLESLEDKQPS----NLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGD 391
            |.      |:||    |....||:||.|||.|||.|||::|||..|..|||:.|||::......|
Zfish   342 KG------KRPSALGNNTLIMDWMPQNDLLGHPKTRAFVAHGGTNGIQEAIYHGVPIIGFGLIFD 400

  Fly   392 QFLNSGAVKQRGFGVIVDFRDFD-SNHITRGLRIILDKKFAERVRRSSEAFRQRPIPPIKLATWW 455
            |..|...::.||....|||...: .:.:|....::.|..:.|.::|.|...:..|:.|:..|.:|
Zfish   401 QPDNLSKMRVRGAAKNVDFATMNKESFLTTVKEVLYDPSYRENMQRLSRLHKDVPVKPLDNAIFW 465

  Fly   456 IEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCRGKISRDT 520
            ||.|:::.||.|:::|:..:.|..|:|:||:|..:..:.|:|:::..:|:.|....|    .|.|
Zfish   466 IEFVMRHKGAAHLRTESYKMPWYSYHSVDVILVLISAVSLIILSIYAVIRYFCCRIC----MRKT 526

  Fly   521 KTK 523
            |.|
Zfish   527 KIK 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	141/485 (29%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	130/454 (29%)
ugt5b2	NP_001170970.2	egt	12..501	CDD:223071	142/489 (29%)
ugt5b2	NP_001170970.2	UDPGT	27..525	CDD:278624	147/517 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584299
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740