DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and ugt5d1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001170967.1	Gene:	ugt5d1 / 100415794	ZFINID:	ZDB-GENE-091118-36	Length:	532	Species:	Danio rerio

Alignment Length:	553	Identity:	158/553 - (28%)
Similarity:	262/553 - (47%)	Gaps:	69/553 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDY 70
            |||.||.|   ......|| |:...| ||:...:.:...|..|||:|::.      :|.:::  |
Zfish    16 LALSAFTL---SCSGGKIL-LYPVDG-SHWVNMKVLIEELHSRGHSITVI------RPKSSW--Y 67

  Fly    71 VFQGMPLLTDIV------DLSNFESEW----------KPLGLPF---KVPTYFML---HDWGLRS 113
            :.:..||.|.|.      |..||..::          :..||.|   :...:.||   |:...:.
Zfish    68 ITEKSPLYTSITIQDNVNDFENFFEDYLSKAMEIERGEGSGLAFLKLQYDLFSMLSTAHEIACKM 132

  Fly   114 CKVALNSPLITQLLKSPIRYDVILLEHFSNDCMAA---VAHLLNAPVIALSSCAIMPWHYKRMGS 175
            ..:.|...::.:.|:.. :||::|    ::..:|.   :||.|..|::     ..:.|.....|.
Zfish   133 VSIILEDKMLVKKLQDE-QYDLML----TDPAIAGGVFLAHYLKLPLV-----LNVRWITSGEGH 187

  Fly   176 PFINPIMPMNFLP-----YTDEMSLIDRLNNFFHFHTVNTLYN-MITQPATDALIAERFGPGLPP 234
            ..|.| .||:::|     :||:|....|:.|.. |.|...|.| .:..|..|.|| :::......
Zfish   188 FAIAP-SPMSYIPLPGSGHTDKMGFAQRVKNVL-FKTFTFLQNRFVVGPHYDILI-DKYLDYKTD 249

  Fly   235 INEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWG 298
            |..:::...:.|:...:....|||..||::.:||.:..|.||||..|......| .:|.|.:|.|
Zfish   250 IVGLIQAADIWLMRADFVFEFPRPTMPNIVYMGGFRCKPSKPLPADLEAFAQSSGEHGFIIMSLG 314

  Fly   299 SMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRA 363
            ::|.|  ||:...:|:..:.::|.:   .:.|:.|........:|....||:||.|||.|.||:|
Zfish   315 TLVKS--LPADMANAIAAAFARLPQ---KVIWRHLGDRPSNVGNNTLIVDWMPQNDLLGHSKIKA 374

  Fly   364 FISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIIL-D 427
            |::|||..|..|||..|||:|..|.:.|||.|...|:.:|.|.|:...:.::....:.||..| |
Zfish   375 FVAHGGTNGVQEAIFHGVPVLGVPLFFDQFDNLIRVQGKGAGKILKLSELNAEAFEQALRESLND 439

  Fly   428 KKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGI 492
            ..:...::..|...|.:|:.|:..|.:||||||::.||.|::||...:.|..|:|:||.|    :
Zfish   440 GSYKRNMQTLSTLHRDQPMRPLDTAIFWIEHVIRHKGATHLRSEFYKMPWYSYHSVDVFL----V 500

  Fly   493 LFLLIVALRKLIKIFKTAFCRGKISRDTKTKTQ 525
            || ::.|:..|..|....:...||....|:|::
Zfish   501 LF-IVAAVCMLSTIAVIRYVCYKICCRRKSKSE 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	142/500 (28%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	125/455 (27%)
ugt5d1	NP_001170967.1	UDPGT	28..527	CDD:278624	150/531 (28%)
ugt5d1	NP_001170967.1	egt	<267..506	CDD:223071	87/248 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584397
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740