DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt5c1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001170966.1	Gene:	ugt5c1 / 100415793	ZFINID:	ZDB-GENE-050419-68	Length:	531	Species:	Danio rerio

Alignment Length:	530	Identity:	144/530 - (27%)
Similarity:	244/530 - (46%)	Gaps:	75/530 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SHFDFFRPMFLALAERGHNISMY----SYFPLEKPVANYTDYVFQGMP------------LLTDI 81
            ||:.....:..||..:||.:.:.    |:|..|    |.|.|....:|            :||..
Zfish    38 SHWVNMDILIKALHGQGHTVDVIRNTNSWFVKE----NSTYYNSITIPDSKGMDEEFVEDVLTKK 98

  Fly    82 VDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLKSPIRYDVI-LLEHFSNDC 145
            :|....:..|  ||   .|..:..:......|.|:...  |||.:.:|.   |:: .|:....|.
Zfish    99 IDYERGKGSW--LG---GVQLFLDVSKAVYESHKLVCR--LITNIFESE---DILKALQEKKYDL 153

  Fly   146 MAA---------VAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPY-----TDEMSLI 196
            |..         :||.|..|::     ..:.|.....|...|.| .||:::|.     ||:||..
Zfish   154 MLTDPGWGTGIILAHKLKLPMV-----YNVRWTTPGEGHFDIAP-SPMSYIPLTGSGNTDKMSFF 212

  Fly   197 DRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPIN--EIVKNTSLMLINQHYALTGPRPY 259
            .|:.|.|::..::...:....|...||..:.|.   ||::  ::::...|.|:...:....|||.
Zfish   213 QRVINVFYYLLLDFQCSRFNVPQYQALCDKYFD---PPVDFYKLLQGADLWLMRVDFVFEFPRPT 274

  Fly   260 APNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKE 323
            .||:|..||.|..|.||||..|.|.:..| .:|||.:|.||.:  :.||....|.:..:.::|.:
Zfish   275 MPNIIYTGGFQCTPTKPLPHDLEDFMQSSGDHGVIVMSLGSFI--SVLPDYVSSEIAAAFARLPQ 337

  Fly   324 YNFVMRWKSLESLEDKQPS----NLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPML 384
                   |.:.....|:||    |....||:||:|||.|||.:.||:|||..|..||::.|||::
Zfish   338 -------KVIWRYTGKKPSTLGNNTLLVDWMPQKDLLGHPKTKLFIAHGGTNGVQEALYHGVPVI 395

  Fly   385 VTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPP 448
            ..||:.||:.|...::.||...||...:...|.:...:: :|.:..:...:::.|...|.:|:.|
Zfish   396 GIPFFFDQYDNLIRLQARGGAKIVSLAELGENSLHAAIQEVINEPSYRLNMQKLSYLHRDKPVEP 460

  Fly   449 IKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCR 513
            :..|.:|||.|:::.||.|:::|:..:.|..|:|:||.:..:.::.:.|.::...::......|
Zfish   461 LDSAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVSVTLIAVVLIFIYSMFVTVRYLCIKCC- 524

  Fly   514 GKISRDTKTK 523
               ||..||:
Zfish   525 ---SRKRKTE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	138/492 (28%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	127/461 (28%)
ugt5c1	NP_001170966.1	UDPGT	28..530	CDD:278624	142/527 (27%)
ugt5c1	NP_001170966.1	egt	<267..507	CDD:223071	82/248 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584389
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.740