DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and ugt5b3

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001348442.1	Gene:	ugt5b3 / 100415792	ZFINID:	ZDB-GENE-100406-5	Length:	534	Species:	Danio rerio

Alignment Length:	525	Identity:	147/525 - (28%)
Similarity:	249/525 - (47%)	Gaps:	66/525 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SHFDFFRPMFLALAERGHNIS---MYSYFPLEKPVANYT------------DYVFQGMPLLTDIV 82
            ||:.....:..||..:||||:   |...:.:::...:||            |::   .|.::.::
Zfish    37 SHWVNMNVLVEALHAKGHNITVMRMADSWYIKEFSPHYTSVNLKSSGGLSEDFI---GPFVSRLM 98

  Fly    83 DLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLIT------QLLKS--PIRYDVILLE 139
            ::....|.|..|.|..::        |......:.:...:||      ||::|  ..::|:||
Zfish    99 NILREGSTWGRLKLEIEM--------WQTSLKMIEIEREMITNMIEDQQLMQSLKKAKFDLIL-- 153

  Fly   140 HFSNDCM---AAVAHLLNAPVIALSSCAIM-PWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLN 200
              ::..|   ..:.|.|..|::......|. ..|:....||.....:||..:|  |.||.::|:.
Zfish   154 --TDPAMYGGVMLGHYLKLPIVYNVRWTIFGEGHFAIAPSPLSYVPVPMLEIP--DRMSFLERVK 214

  Fly   201 NFFHFHTVNTLYNMITQPATDALIAERF-GPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVI 264
            |...:....|....:..|..:|| .||| ||.: ....:|:...|.|....:....|||..||::
Zfish   215 NVVMYIITETQIAFLIAPTYNAL-CERFIGPEV-NFGNLVQEADLWLHRADFVFEYPRPTMPNIV 277

  Fly   265 EVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVM 328
            .:.|.|..|.|||||.|.|.:..| .:|||.:|.|:::..  ||.....|:.::.::|.: ..:.
Zfish   278 YMAGFQCKPSKPLPQDLEDFVQSSGDHGVIVMSLGTLIGQ--LPDDVAEAIAEAFAELPQ-KIIW 339

  Fly   329 RWKSLESLEDKQPS----NLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFY 389
            |:|.      |:||    |....||:||.|||.|||.|||::|||..|..|||:.|||::.....
Zfish   340 RYKG------KRPSALGNNTLVMDWMPQNDLLGHPKTRAFVAHGGTNGVQEAIYHGVPIIGFGLI 398

  Fly   390 GDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIPPIKLAT 453
            .||..|...::.||....|||...|.....:.:: ::.|..:.|.::|.|...:..|:.|:..|.
Zfish   399 FDQPDNLSKMRVRGAAKNVDFATMDKESFLKTVKEVLYDPSYRENMQRLSRLHKDVPVKPLDNAI 463

  Fly   454 WWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCRGKISR 518
            :|||.|:::.||.|:::|:..:.|..|:|:||:|..:..:.|:|:::..:|:.|....|    .|
Zfish   464 FWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVILVLISAVSLIILSIYAVIRYFCCRIC----MR 524

  Fly   519 DTKTK 523
            .||.|
Zfish   525 TTKNK 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	137/487 (28%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	126/456 (28%)
ugt5b3	NP_001348442.1	UDPGT	27..531	CDD:278624	147/525 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584297
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740