DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt2b5

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001170816.2	Gene:	ugt2b5 / 100384902	ZFINID:	ZDB-GENE-100402-3	Length:	527	Species:	Danio rerio

Alignment Length:	520	Identity:	142/520 - (27%)
Similarity:	232/520 - (44%)	Gaps:	72/520 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SHFDFFRPMFLALAERGHNISM------------------YSYFPLEKPVANYTDYVFQGMPLLT 79
            ||:...:.:...|.:||||:::                  |.:|.:.|...:..|:..:.|....
Zfish    30 SHWINLKIVLDTLLDRGHNVTVLVPDGALFMKAKESDRFSYQHFSVSKSAQDMQDFFDELMRFSV 94

  Fly    80 DIVDLSNFESEWKPLGLPFKVPTYFML----HDWGLRSCKVALNSPLITQLLKSPIRYDVILLEH 140
            ..:|.|:|      |.:..|   :|.|    .|..|..|...|.||.:...||.. ::||:|.:.
Zfish    95 FEMDNSSF------LEIQMK---FFNLGSQHQDMSLSYCDGILKSPELMDKLKKG-KFDVVLSDP 149

  Fly   141 FSNDCMAAVAHLLNAPVI----------ALSSCAIMPWHYKRMGSPFINPIMPMNFLP-----YT 190
            . ..|...||..||.|::          |...|..:|              .|.:::|     .|
Zfish   150 M-YPCSDIVAEELNVPLVYTFRFSVAHAAERMCGQIP--------------APPSYVPGAMSKLT 199

  Fly   191 DEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTG 255
            |:||..:|:.|...:.:.:||..:|.: ..|....|.||.. ....|::....:.||..::....
Zfish   200 DKMSFTERIFNMLFYLSQDTLSRLIWR-RFDNYYTEYFGRS-TSYCEMMGKADIWLIRTYWDFEF 262

  Fly   256 PRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSALFQSIS 319
            |||:.||...:|||...|.||||:.:.:.:..| .:|::..:.|||::.  :|....:.:..:::
Zfish   263 PRPFVPNFKYIGGLHCTPAKPLPKDMEEFVQSSGDDGIVVFTLGSMIDK--VPKEMSNRIASALA 325

  Fly   320 QLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPML 384
            |:.:   .:.|:......|....|...:.|:||.|||.|||.||||:|||..|..|||:.||||:
Zfish   326 QIPQ---KVLWRYGGEKPDTLGENTRIYKWIPQNDLLGHPKTRAFITHGGTNGVYEAIYHGVPMV 387

  Fly   385 VTPFYGDQFLNSGAVKQRGFGVIVD-FRDFDSNHITRGLR-IILDKKFAERVRRSSEAFRQRPIP 447
            ..|.:|||..|...:..|...|:|| .:......:...|. :|.|..:.|...|.|.....||:.
Zfish   388 GIPLFGDQPDNMVHMTTRAAAVVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLSRIHHDRPMK 452

  Fly   448 PIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFC 512
            |:..:.:|||.|::..||.|::.||.::.|..|:.:||..|...:|.|::....|:.|.|....|
Zfish   453 PLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYHCLDVFAFLTTVLTLVLYICFKMAKFFIMRCC 517

Fly 513 512
Zfish 518 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	135/493 (27%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	124/462 (27%)
ugt2b5	NP_001170816.2	UDPGT	20..523	CDD:278624	142/520 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810