DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt36F1 and ugt2a3

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001170814.2	Gene:	ugt2a3 / 100384900	ZFINID:	ZDB-GENE-080721-22	Length:	532	Species:	Danio rerio

Alignment Length:	542	Identity:	157/542 - (28%)
Similarity:	257/542 - (47%)	Gaps:	82/542 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PGK-SHFDFFRPMFLALAERGHNISM------------------YSYFP--LEKPVAN--YTDYV 71
            ||: ||:...|.:..||.:|.|::::                  |..|.  :||..|:  ::|::
Zfish    27 PGEYSHWHNMRAIIEALVDRNHSVTVLVGSSSPTVPHTQKARFDYHVFKVNIEKEEADAVWSDFI 91

  Fly    72 FQGM-PLLTDIVDLSNFESEWKPLGLPFKVPTYFM-LHDWGLRSCKVALNSPLITQLLKSPIRYD 134
            :..| ...|....:||.          |:|.:.|| |.|   ..||......|:..|.:|  .||
Zfish    92 YLWMNETATKYETVSNI----------FQVMSRFMTLTD---EVCKGMFKEDLLQMLRES--HYD 141

  Fly   135 VILLEHFSN---DCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLP-------Y 189
            |:    ||:   .|...:|..||.|:: ||..|...:.::||....  | .|.:::|       .
Zfish   142 VL----FSDPMMPCSDLMAQTLNIPLV-LSLRATFAYSFERMCGQM--P-APPSYVPAASLRDHL 198

  Fly   190 TDEMSLIDRLNN---FFHFHTVNTLYNMITQPATDALIAERFGPGLPPIN--EIVKNTSLMLINQ 249
            ||.||.::|:.|   :|.......||.|.|   .|.:..|..|   .|..  |.:....:.||..
Zfish   199 TDRMSFMERVENMLLYFSHDVFFKLYMMFT---FDRIYTEIRG---KPTTMCETMGKADIWLIRT 257

  Fly   250 HYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNSNTLPSGKRSA 313
            ::....|||:.||...||||...|.|||.:.:.:.:..| .:||:..|.|||:.:  |.|.:.:.
Zfish   258 YWDFEYPRPFPPNFKFVGGLHCKPAKPLSKEMEEFVQSSGDHGVVVFSLGSMIKN--LTSERANT 320

  Fly   314 LFQSISQLKEYNFVMRW--KSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEA 376
            :..::.|:.: ..|.|:  |:.|:|    ..|...:||:||.|||.|||.:|||:|||..|..||
Zfish   321 IAAALGQIPQ-KVVWRYSGKTPETL----APNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEA 380

  Fly   377 IHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDK-KFAERVRRSSEA 440
            |:.||||:..|.:.||..|...:|.:|..|::|....:|..:...|:.:|:. .:.|.:.|.|..
Zfish   381 IYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRI 445

  Fly   441 FRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLL-IVALRKLI 504
            ...:|:.|:..|.:|||.|::..||.|::.:|..::|..|:.:||..|.|.|..|: .:.::...
Zfish   446 HHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIAALITFLWVKACC 510

  Fly   505 KIFKTAFCRGKISRDT-KTKTQ 525
            .:|:....:.:..|.| |:|.:
Zfish   511 FLFRRCVRKTRPERKTQKSKNE 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	148/500 (30%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	136/465 (29%)
ugt2a3	NP_001170814.2	UDPGT	21..519	CDD:278624	153/527 (29%)
		REC	<129..>178	CDD:302758	16/55 (29%)
		egt	<254..485	CDD:223071	81/237 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584377
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930