DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt36F1 and ugt5e1

DIOPT Version :9

Sequence 1:	NP_609909.1	Gene:	Ugt36F1 / 35137	FlyBaseID:	FBgn0027074	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_005166829.1	Gene:	ugt5e1 / 100002993	ZFINID:	ZDB-GENE-081105-106	Length:	590	Species:	Danio rerio

Alignment Length:	545	Identity:	151/545 - (27%)
Similarity:	248/545 - (45%)	Gaps:	73/545 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYS-----YFPLEKP 63
            ||...||..:...|.|.:|.|.:            ..:...|.:|||.:::..     |.|  :.
Zfish    75 LPSLSLAGKILVYPVDGSHWLNM------------NILLQELHQRGHKLTVVRSANSWYIP--EN 125

  Fly    64 VANYTDYVFQ--GMPLLTDIVDLSNF-----------ESEWKPLGLPFKVPTYF-MLHDWGLRSC 114
            ..:||....|  .:..|.|...:::|           .|.|..|.|..::.|.. ..|.......
Zfish   126 ATHYTSITIQVNHLSSLEDPKYMASFLKRNIDIQRGKGSIWSFLALQKEIITLLEESHRSTAEMV 190

  Fly   115 KVALNSPLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFIN 179
            :|.|....:.:.||.. :||::|     .|...|...:|.| .:.|.....:.|.....|...|.
Zfish   191 RVVLEDEKLIKTLKES-KYDLML-----TDPGFAGGVILGA-YLGLPMVFNVRWITNAEGHFAIA 248

  Fly   180 PIMPMNFLP-----YTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIV 239
            | .|::::|     .||:||..::|.|..||.....:.:|:|:|....:|::...|. ..:..::
Zfish   249 P-SPLSYIPTIGSRVTDKMSFANKLKNIMHFGIGQYIDHMLTRPLYQGVISKYIDPN-TNVYALI 311

  Fly   240 KNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRS-PNGVIYISWGSMVNS 303
            :...|.|:...:....|||..|||:.:||.|..|.||||..|...::.| .:||:.:|.|:::.|
Zfish   312 QGADLWLMRVDFVFEFPRPTMPNVVYIGGFQCKPSKPLPDELNKFVESSGEHGVVIMSLGTLLGS 376

  Fly   304 NTLPSGKRSALFQSISQLKEYNFV-----MRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRA 363
                      |...||::....|.     :.|:.:........:|....|||||.|||.|||.:|
Zfish   377 ----------LVPDISEIVASAFAQLPQKVIWRHVGEKPSTLGNNTLVVDWLPQNDLLGHPKTKA 431

  Fly   364 FISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDK 428
            |::|||..|..|||:.|||||..|...|||.|...::.||...::|....|.:.:|:.|:.|||:
Zfish   432 FVTHGGTNGIYEAIYHGVPMLGLPLIFDQFDNIIRLEARGVARMLDVATLDVDILTQALKDILDE 496

  Fly   429 K--FAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWL- 490
            |  :.:.:|:.|...|..|:.|:..|.:|:|.|:::.||.|:::|:..:.|..|:.:|||...:
Zfish   497 KQSYQKNMRKMSSLHRDTPLKPLDSAIFWLEFVMRHKGAAHLRTESYKLPWYSYHCLDVLALIMS 561

  Fly   491 -----GILFLLI--VALRKLIKIFK 508
                 |:|.:||  ..||..::..|
Zfish   562 LCTAAGLLLILISRALLRACVRKIK 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt36F1	NP_609909.1	egt	19..487	CDD:223071	138/499 (28%)
Ugt36F1	NP_609909.1	YjiC	38..461	CDD:224732	127/454 (28%)
ugt5e1	XP_005166829.1	UDPGT	82..586	CDD:278624	146/536 (27%)
ugt5e1	XP_005166829.1	egt	<324..550	CDD:223071	81/235 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584273
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740