DRSC/TRiP Functional Genomics Resources

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Protein Alignment ham and ZNF333

DIOPT Version :9

Sequence 1:NP_724130.4 Gene:ham / 35135 FlyBaseID:FBgn0045852 Length:1108 Species:Drosophila melanogaster
Sequence 2:NP_115809.1 Gene:ZNF333 / 84449 HGNCID:15624 Length:665 Species:Homo sapiens


Alignment Length:304 Identity:82/304 - (26%)
Similarity:120/304 - (39%) Gaps:68/304 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   286 KSGGGGSSAPSDDRSDRDNGSLYSGDEFSKDKKNSSLIREGDIDFTDDENGFDIRCEVCDKVYPD 350
            :||....:....::|.|     ||.|....:|.:::            |..||  |:.|.:.:..
Human   360 RSGDKSYACNKCEKSFR-----YSSDLIRHEKTHTA------------EKCFD--CQECGQAFKY 405

  Fly   351 LDLLDDHLIGAHHFKQDEFPCKQCALRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQR 415
            ...|..|:  ..|..:..|.|.||...|.....||.|:. :|...:.|.|::|.|.|..||:|:.
Human   406 SSNLRRHM--RTHTGEKPFECSQCGKTFTRNFNLILHQR-NHTGEKPYECKDCGKAFNQPSSLRS 467

  Fly   416 HIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMH--- 477
            |:|. |.|.:...|.:|||.|...|.||.|...|:..||:.|..|.|.:...::|..|||:|   
Human   468 HVRT-HTGEKPFECSQCGKAFREHSSLKTHLRTHTREKPYECNQCGKPFRTSTHLNVHKRIHTGE 531

  Fly   478 -----ATCRMQIK-------------------CDKCNQSFSTLTSLTKHKKFCDSTGPGPYRNQH 518
                 |||...:.                   |.:|.::||..:||.||.:  ..:|..||..|.
Human   532 KLYECATCGQVLSRLSTLKSHMRTHTGEKPYVCQECGRAFSEPSSLRKHAR--THSGKKPYACQE 594

  Fly   519 VNR------H---HQHPHQHPLPHQPHLAATATSTCPAPPRESS 553
            ..|      |   |...|....|:|       .:.|....|.||
Human   595 CGRAFGQSSHLIVHVRTHSAGRPYQ-------CNQCEKAFRHSS 631

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hamNP_724130.4 PR-SET_ZFPM 131..253 CDD:380978
C2H2 Zn finger 341..363 CDD:275368 4/21 (19%)
C2H2 Zn finger 371..392 CDD:275368 7/20 (35%)
SFP1 <391..479 CDD:227516 33/95 (35%)
C2H2 Zn finger 400..421 CDD:275368 9/20 (45%)
SUF4-like 403..>445 CDD:411020 18/41 (44%)
C2H2 Zn finger 403..421 CDD:411020 8/17 (47%)
C2H2 Zn finger 429..449 CDD:275368 9/19 (47%)
C2H2 Zn finger 457..477 CDD:275368 7/19 (37%)
C2H2 Zn finger 486..504 CDD:275368 8/17 (47%)
PTZ00121 <641..>728 CDD:173412
COG5048 935..>1028 CDD:227381
zf-C2H2 935..957 CDD:395048
C2H2 Zn finger 937..957 CDD:275368
zf-H2C2_2 949..973 CDD:404364
C2H2 Zn finger 965..986 CDD:275368
C2H2 Zn finger 994..1014 CDD:275368
ZNF333NP_115809.1 KRAB 4..61 CDD:214630
KRAB 4..41 CDD:279668
KRAB 203..263 CDD:214630
KRAB 203..242 CDD:279668
COG5048 <228..525 CDD:227381 53/187 (28%)
C2H2 Zn finger 340..360 CDD:275368 82/304 (27%)
zf-C2H2 366..388 CDD:278523 6/26 (23%)
C2H2 Zn finger 368..388 CDD:275368 6/24 (25%)
zf-C2H2 394..416 CDD:278523 6/25 (24%)
C2H2 Zn finger 396..416 CDD:275368 4/21 (19%)
zf-H2C2_2 408..433 CDD:290200 8/26 (31%)
C2H2 Zn finger 424..444 CDD:275368 7/20 (35%)
zf-H2C2_2 436..461 CDD:290200 9/25 (36%)
C2H2 Zn finger 452..472 CDD:275368 9/20 (45%)
zf-H2C2_2 464..487 CDD:290200 9/23 (39%)
C2H2 Zn finger 480..500 CDD:275368 9/19 (47%)
zf-H2C2_2 492..517 CDD:290200 9/24 (38%)
C2H2 Zn finger 508..528 CDD:275368 7/19 (37%)
zf-H2C2_2 520..545 CDD:290200 8/24 (33%)
C2H2 Zn finger 536..556 CDD:275368 3/19 (16%)
zf-H2C2_2 549..572 CDD:290200 2/22 (9%)
C2H2 Zn finger 564..584 CDD:275368 8/21 (38%)
zf-H2C2_2 576..599 CDD:290200 9/24 (38%)
zf-C2H2 590..612 CDD:278523 5/21 (24%)
C2H2 Zn finger 592..612 CDD:275368 4/19 (21%)
zf-C2H2 618..640 CDD:278523 5/21 (24%)
C2H2 Zn finger 620..640 CDD:275368 4/12 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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