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Protein Alignment ham and ZNF484

DIOPT Version :9

Sequence 1:	NP_724130.4	Gene:	ham / 35135	FlyBaseID:	FBgn0045852	Length:	1108	Species:	Drosophila melanogaster
Sequence 2:	XP_011517375.1	Gene:	ZNF484 / 83744	HGNCID:	23385	Length:	884	Species:	Homo sapiens

Alignment Length:	724	Identity:	156/724 - (21%)
Similarity:	228/724 - (31%)	Gaps:	256/724 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   307 LYSGD---EFSKDKKNSSLIREGDIDFTDDENGFDIRCEVCDKVYPDLDLLDDHLIGAHHFKQDE 368
            ::||:   |:|:.:||.......:|.......|....|..|.|.:.....|..|  ...|..:..
Human   381 IHSGEKPYEYSECEKNLPQNSNLNIHKKIHTGGKHFECTECGKAFTRKSTLSMH--QKIHTGEKP 443

  Fly   369 FPCKQCALRFCHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECG 433
            :.|.:|...|..:...|.||.| |...:.|.|.:|.|.|...|.|..|.| .|.|.....|.|||
Human   444 YVCTECGKAFIRKSHFITHERI-HTGEKPYECSDCGKSFIKKSQLHVHQR-IHTGENPFICSECG 506

  Fly   434 KTFGTSSGLKQHQHIHSSVKPFACEVCSKAYTQFSNLCRHKRMHATCRMQIKCDKCNQSFSTLTS 498
            |.|...:.|..||.||:..:|:.|.||.||:|..|||.:|:::| |.....||..|.:||:..:.
Human   507 KVFTHKTNLIIHQKIHTGERPYICTVCGKAFTDRSNLIKHQKIH-TGEKPYKCSDCGKSFTWKSR 570

  Fly   499 LTKHKKFCDSTGPGPYRNQHVNRHHQHPHQHPLPHQPHLAATATSTCPAPPRESSESSSSAAAAA 563
            |..|:| | .||         .||:                           |.||...:....:
Human   571 LRIHQK-C-HTG---------ERHY---------------------------ECSECGKAFIQKS 597

  Fly   564 VAAMSTPPNPFLMFRTAPSFFPGFPPYGFPPFLPQNPLHPTNIPMFFSKNPMDLGCGGPEITSPV 628
            ..:|                              ...:|....|...::      ||
Human   598 TLSM------------------------------HQRIHRGEKPYVCTE------CG-------- 618

  Fly   629 SAFDQKLPFGFLKGENSESQAYDKVTEKELVFKAEEKLKKEPLVQAFEGEEDESRSSLDIKGKLE 693
            .||..|..|               :|.
Human   619 KAFFHKSHF---------------ITH-------------------------------------- 630

  Fly   694 DTRNDSKSEEQDDMKQEPERVSTPDQQQAEDDRKSIDIMSTPPPADTPSGGDGPLDLSICRKRSA 758
                              ||:.|                           |:.|.:.|||
Human   631 ------------------ERIHT---------------------------GEKPYECSIC----- 645

  Fly   759 GSFFTAPAEDNLMLHRFMPRLHEFE-----AERGQPLKMRKSHSSAESSTSQKSHKGSSPTPTPT 818
            |..||..::  |.:|:   ::|..|     ||.|:....|     :...|.||.|.|..|.....
Human   646 GKSFTKKSQ--LHVHQ---QIHTGEKPYRCAECGKAFTDR-----SNLFTHQKIHTGEKPYKCSD 700

  Fly   819 ASPGLTPSPS----PPTSAGGELSSTSEGGAVPTMAAAAFAADHSALASGPTLPQTHPTFHPLLL 879
            .....|....    ..:..|......||.|              .|.|...||         ::.
Human   701 CGKAFTRKSGLHIHQQSHTGERHYECSECG--------------KAFARKSTL---------IMH 742

  Fly   880 EEIYRSGFPFLCQPGGRRGIEALLAGAASAAAPKRPLPPVKFSAGSVVGLKTKDR-YSCKFCGKV 943
            :.|:....|::|...|:..|:                   |........:.|.:: |.|..|||.
Human   743 QRIHTGEKPYICNECGKSFIQ-------------------KSHLNRHRRIHTGEKPYECSDCGKS 788

  Fly   944 FPRSANLTRHLRTHTGEQPYPCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRSFGQQTNLD 1008
            |.:.:.|..|.|.||||:||.|..|.:||:|.|||.:| :.||.|::|::|....::...:..|.
Human   789 FIKKSQLHEHHRIHTGEKPYICAECGKAFTIRSNLIKH-QKIHTKQKPYKCSDLGKALNWKPQLS 852

  Fly  1009 RHVKKHESE 1017
            ...|....|
Human   853 MPQKSDNGE 861

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.